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(2-HYDROXYETHYL)TRIPHENYLPHOSPHONIUM BROMIDE

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Origin: China

Cas No: 7237-34-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 7237-34-5 Formula: C20H20BrOP Molecular Weight: 387.25000

Description

(2-Hydroxyethyl)triphenylphosphonium Bromide has cytotoxic activity against the growth of tissue culture cells originating from human epidermoid carcinoma of the nasopharynx (KB). It is commonly used as a Wittig reagent.

Basic Info

Chemical Name	(2-HYDROXYETHYL)TRIPHENYLPHOSPHONIUM BROMIDE
Synonyms	2-hydroxyethyl(triphenyl)phosphanium,bromide;
CAS No.	7237-34-5
Molecular Formula	C20H20BrOP
Molecular Weight	387.25000
PSA	33.82000
LogP	-0.02320

Properties

Appearance & Physical State	white powder
Density	1.26g/cm3
Boiling Point	499.5ºC at 760 mmHg
Melting Point	217-219ºC(lit.)
Flash Point	255.9ºC
Refractive Index	1.591
Storage Condition	0-6ºC

Safety Info

Safety Statements	S26-S36
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi
Hazard Declaration	H315; H319; H335
Symbol	GHS07
Caution Statement	P261; P305 + P351 + P338
Signal Word	Warning

Synthesis Route

Triphenylphosphine hydrobromide+2-(3-bromo-4-methoxyphenyl)-1,3-dioxolane→3-Bromo-4-methoxybenzaldehyde+(2-HYDROXYETHYL)TRIPHENYLPHOSPHONIUM BROMIDE
2-(4-(benzyloxy)phenyl)-1,3-dioxolane+Triphenylphosphine hydrobromide→4-Benzyloxybenzaldehyde+(2-HYDROXYETHYL)TRIPHENYLPHOSPHONIUM BROMIDE
Triphenylphosphine hydrobromide+2-(naphth-1-yl)-1,3-dioxolane→1-naphthaldehyde+(2-HYDROXYETHYL)TRIPHENYLPHOSPHONIUM BROMIDE

Precursor

2-Bromoethanol
(4-(1,3-dioxolan-2-yl)phenoxy)(tert-butyl)diphenylsilane
Triphenyl(vinyl)phosphonium bromide
Triphenylphosphine

Downstream Product

(2-Methoxyethyl)triphenylphosphonium bromide
TRANS-2-PENTEN-1-OL
2-bromoethyl(triphenyl)phosphanium,bromide
Triphenyl(vinyl)phosphonium bromide

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