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2'-HYDROXY-4,4',6'-TRIMETHOXYCHALCONE

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Origin: China

Cas No: 3420-72-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 3420-72-2 Formula: C18H18O5 Molecular Weight: 314.33300

Basic Info

Chemical Name	2'-HYDROXY-4,4',6'-TRIMETHOXYCHALCONE
Synonyms	FLAVOKAWIN A; Flavokavin A; 2'-Hydroxy-4,4',6'-trimethoxy-trans-chalcone; 2'-Hydroxy-4,4',6'-trimethoxy; flavokawain-A; 2'-hydroxy-4',6'-dimethoxyphenyl-4-methoxystyrylketone; 2'-hydroxy-4,4',6'-trimethoxy-chalcone;
CAS No.	3420-72-2
Molecular Formula	C18H18O5
Molecular Weight	314.33300
PSA	64.99000
LogP	3.31410

Properties

Density	1.207g/cm3
Boiling Point	529.9ºC at 760mmHg
Melting Point	112-116ºC(lit.)
Flash Point	193.2ºC
Refractive Index	1.599

Safety Info

Safety Statements	26-36
HS Code	2914509090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

4',6'-Dimethoxy-2'-hydroxyacetophenone+Anisic aldehyde→2'-HYDROXY-4,4',6'-TRIMETHOXYCHALCONE
(2E)-1-(2,4,6-trimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one→2'-HYDROXY-4,4',6'-TRIMETHOXYCHALCONE
1,3,5-trimethoxybenzene+4-METHOXYCINNAMOYL CHLORIDE→2'-HYDROXY-4,4',6'-TRIMETHOXYCHALCONE

Precursor

4',6'-Dimethoxy-2'-hydroxyacetophenone
1,3,5-trimethoxybenzene
(2E)-1-(2,4,6-trimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one
Anisic aldehyde

Downstream Product

tangeretin
5-hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)chromen-4-one
(S)-naringenin
apigenin 7,4'-dimethyl ether

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