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2-Hydroxy-4-(trifluoromethyl)benzoic acid

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Origin: China

Cas No: 328-90-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
328-90-5
Other Names:
4-Trifluoromethyl Salicylic Acid
MF:
C8H5F3O3
EINECS No.:
no
Place of Origin:
China
Type:
Pharmaceutical Intermediates
Purity:
>99%
Brand Name:
samreal
Application:
organic synthsis
color:
White or almost white
Packaging&Delivery
Packaging Details
drum
Port
Ningbo

Property

CAS No.: 328-90-5 Formula: C8H5F3O3 Molecular Weight: 206.11900

Description

The active metabolite of Triflusal; inhibits cardiac hypertrophy in vitro and in vivo by blocking the NF-κB signaling pathway.

Basic Info

Chemical Name	2-Hydroxy-4-(trifluoromethyl)benzoic acid
Synonyms	2-Hydroxy-4-(trifluoromethyl)benzoic Acid; 4-Trifluoromethylsalicylic acid; 4-Trifluoromethyl Salicylic Acid; 2-hydroxy-4-trifluoromethyl benzoic acid; Triflusal impurity B; 4-(TrifluoroMethyl)salicylic Acid; 4-Tfmsa;
CAS No.	328-90-5
Molecular Formula	C8H5F3O3
Molecular Weight	206.11900
PSA	57.53000
LogP	2.10920

Properties

Density	1.539 g/cm3
Boiling Point	286.4ºCat 760 mmHg
Melting Point	178ºC
Flash Point	127ºC
Refractive Index	1.509

Safety Info

Safety Statements	S26; S36/37/39
HS Code	2918290000
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

4-trifluoromethylbenzoic acid→2-Hydroxy-4-(trifluoromethyl)benzoic acid
2-methoxymethoxy-4-(trifluoromethyl)benzene→2-Hydroxy-4-(trifluoromethyl)benzoic acid
carbon dioxide+3-Trifluoromethylphenol→2-Hydroxy-4-(trifluoromethyl)benzoic acid

Precursor

3-Trifluoromethylphenol
carbon dioxide
2-methoxymethoxy-4-(trifluoromethyl)benzene
4-trifluoromethylbenzoic acid

Downstream Product

2-hydroxy-4-methoxycarbonylbenzoic acid
2-Hydroxyterephthalic Acid
2-acetyloxy-4-(trifluoromethyl)benzoic acid
methyl 2-hydroxy-4-(trifluoromethyl)benzoate

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