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2-(chloromethyl)oxirane,2-methyl-1H-imidazole

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Origem: China

Cas No: 95522-45-5

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 50 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Descrição do produto

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CAS No.: 95522-45-5 Formula: C6H9ClN2O Molecular Weight: 160.60100

Description

Colestilan (INN, trade name BindRen) is a medication that acts as a phosphate binder and bile acid sequestrant. It is an ion-exchange resin, is an orally administered bile acid sequestrant that is being developed by Mitsubishi Tanabe Pharma Corporation for the treatment of hypercholesterolaemia and hyperphosphataemia. It has been launched in Japan for hypercholesterolaemia. For the treatment of hyperphosphataemia, it is launched in Austria, Germany, the Czech Republic, Portugal and the United Kingdom, is registered in the EU. Phase III development in paediatric patients with hyperphosphataemia associated with chronic kidney disease was underway in the UK and Germany. However, the company discontinued the development. In addition, the phase II development in type-2 diabetes mellitus and phase I development in hyperphosphataemia, in Japan, was also discontinued by the company.
Phase III development for hyperphosphataemia was previously underway in the US. However, Mitsubishi Tanabe Pharma discontinued development in this market. Colestilan was also investigated in phase III trials in Europe and Asia for hypercholesterolaemia. However, as of March 2015, no recent reports of development have been identified for the drug in this indication

Basic Info

Chemical Name	2-(chloromethyl)oxirane,2-methyl-1H-imidazole
Synonyms	Colestimide; Epichlorohydrin-2-methylimidazole copolymer; MCI 196; Colestilan; Cholebine;
CAS No.	95522-45-5
Molecular Formula	C6H9ClN2O
Molecular Weight	160.60100
PSA	29.04000
LogP	-3.31200