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Picture of 2-(chloromethyl)oxirane,2-methyl-1H-imidazole

2-(chloromethyl)oxirane,2-methyl-1H-imidazole

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Origin: China

Cas No: 95522-45-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 95522-45-5 Formula: C6H9ClN2O Molecular Weight: 160.60100

    Description

    Colestilan (INN, trade name BindRen) is a medication that acts as a phosphate binder and bile acid sequestrant. It is an ion-exchange resin, is an orally administered bile acid sequestrant that is being developed by Mitsubishi Tanabe Pharma Corporation for the treatment of hypercholesterolaemia and hyperphosphataemia. It has been launched in Japan for hypercholesterolaemia. For the treatment of hyperphosphataemia, it is launched in Austria, Germany, the Czech Republic, Portugal and the United Kingdom, is registered in the EU. Phase III development in paediatric patients with hyperphosphataemia associated with chronic kidney disease was underway in the UK and Germany. However, the company discontinued the development. In addition, the phase II development in type-2 diabetes mellitus and phase I development in hyperphosphataemia, in Japan, was also discontinued by the company.
    Phase III development for hyperphosphataemia was previously underway in the US. However, Mitsubishi Tanabe Pharma discontinued development in this market. Colestilan was also investigated in phase III trials in Europe and Asia for hypercholesterolaemia. However, as of March 2015, no recent reports of development have been identified for the drug in this indication

    Basic Info

    Chemical Name 2-(chloromethyl)oxirane,2-methyl-1H-imidazole
    Synonyms

    Colestimide;
    Epichlorohydrin-2-methylimidazole copolymer;
    MCI 196;
    Colestilan;
    Cholebine;

    CAS No. 95522-45-5
    Molecular Formula C6H9ClN2O
    Molecular Weight 160.60100
    PSA 29.04000
    LogP -3.31200

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