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(2-butyl-5-nitro-1-benzofuran-3-yl)-(4-methoxyphenyl)methanone

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Origem: China

Cas No: 141627-42-1

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 50 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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Especificação de produtos
Descrição do produto

Quick Details
CAS No.:
141627-42-1
Other Names:
2-Butyl-3-(4-Methoxybenzoyl)-5-Nitrobenzofuran
MF:
C20H19NO5
EINECS No.:
141627-42-1
Place of Origin:
Fujian, China
Type:
Syntheses Material Intermediates
Purity:
99%
Brand Name:
SIMAGCHEM
Model Number:
SC19980
Application:
Dronedarone
Appearance:
Off-white crystalline
Packaging&Delivery
Packaging Details
As demand
Port
Shanghai
Lead Time:
Quantity(Grams) 1 - 1 >1
Est. Time(days) 4 To be negotiated

Property

CAS No.: 141627-42-1 Formula: C20H19NO5 Molecular Weight: 353.36900

Description

(2-Butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone is a reagent in the preparation of heterocyclic benzofuran carboxamides via amidation of heterocyclic acyl chlorides with benzofuranamine. This is also a derivative of Dronedarone,which is a drug used for the treatment of atrial fibrillation and atrial flutter in patients who have suffered cardiac arrhythmias.

Basic Info

Chemical Name	(2-butyl-5-nitro-1-benzofuran-3-yl)-(4-methoxyphenyl)methanone
Synonyms	QC-8893; CL4580;
CAS No.	141627-42-1
Molecular Formula	C20H19NO5
Molecular Weight	353.36900
PSA	85.26000
LogP	5.44640

Properties

Appearance & Physical State	Off-white crystalline
Density	1.235 g/cm3
Boiling Point	537.726ºC at 760 mmHg
Refractive Index	1.603
Vapor Pressure	0mmHg at 25°C

Safety Info

HS Code	2932999099

Synthesis Route

4-methoxybenzoic acid+2-Butyl-5-nitrobenzofuran→(2-butyl-5-nitro-1-benzofuran-3-yl)-(4-methoxyphenyl)methanone
4-Methoxybenzoyl chloride+2-Butyl-5-nitrobenzofuran→(2-butyl-5-nitro-1-benzofuran-3-yl)-(4-methoxyphenyl)methanone
2-(2-pentanoyloxy-5-nitrophenyl)-1-(4-methoxyphenyl)-ethanone→(2-butyl-5-nitro-1-benzofuran-3-yl)-(4-methoxyphenyl)methanone

Precursor

4-methoxybenzoic acid
4-Methoxybenzoyl chloride
2-Butyl-5-nitrobenzofuran
2-(2-pentanoyloxy-5-nitrophenyl)-1-(4-methoxyphenyl)-ethanone

Downstream Product

(5-amino-2-butyl-1-benzofuran-3-yl)-[4-[3-(dibutylamino)propoxy]phenyl]methanone
2-(n-butyl)-3-(2-hydroxybenzoyl)-5-nitrobenzofuran
(2-butyl-5-nitro-1-benzofuran-3-yl)-[4-[3-(dibutylamino)propoxy]phenyl]methanone
(2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxyphenyl)methanone

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