Home > Aminoacid Compounds> 2-aminoisobutyric acid

2-aminoisobutyric acid

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 62-57-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Property

CAS No.: 62-57-7 Formula: C4H9NO2 Molecular Weight: 103.12000

Description

2-Aminoisobutyric acid, or α-aminoisobutyric acid (AIB) or α-methylalanine or 2-methylalanine, is an amino acid with the structural formula is H2N-C(CH3)2-COOH. It is contained in some antibiotics of fungal origin, e.g. alamethicin and some lantibiotics. It is not one of the proteinogenic amino acids and rather rare in nature (cf. Non-proteinogenic amino acids). α-Aminoisobutyric acid is a strong helix inducer in peptides. Oligomers of AIB form 310 helices.
In the laboratory, 2-aminoisobutyric acid may be prepared from acetone cyanohydrin, by reaction with ammonia followed by hydrolysis.

Basic Info

Chemical Name	2-aminoisobutyric acid
Synonyms	2-amino-2-methylpropanoic acid; 2-Amino-2-methylpropionic acid; Alanine, 2-methyl-; 2-Aminoisobutyric acid; 2-methyl-2-aminopropanoic acid;
CAS No.	62-57-7
Molecular Formula	C4H9NO2
Molecular Weight	103.12000
PSA	63.32000
LogP	0.50860

Properties

Appearance & Physical State	White crystalline powder
Density	1.109 g/cm3
Boiling Point	204.4ºC at 760 mmHg
Melting Point	335ºC
Flash Point	77.4ºC
Refractive Index	1.464
Water Solubility	SOLUBLE
Stability	Stable under normal temperatures and pressures.
Storage Condition	Store at RT.

Safety Info

RTECS	AY7000000
Safety Statements	S22-S24/25
HS Code	29224995
WGK Germany	3

Synthesis Route

Sulfuric acid+4-AMINO-4-METHYL-2-PENTANONE HYDROGENOXALATE→formic acid+2-aminoisobutyric acid
Ac-Aib-Aib-Val-Aib-Val-Aib-Aib-Ala-Aib-prolinol→L-alanine+L-valine
trichoderin A→L-valine+L-isoleucine

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Intraperitoneal	LD - Lethal dose	Rodent - rat	>2500 mg/kg	1.Details of toxic effects not reported other than lethal dose value

Precursor

acetone
Proc-Aib-OH
α-methylalanine methyl ester
5,5-Dimethylhydantoin

Downstream Product

ethyl 2-amino-2-methylpropanoate
2-(9H-fluoren-9-ylmethoxycarbonylamino)-2-methylpropanoic acid
2-(2-cyanoethylamino)-2-methylpropanoic acid
tert-butyl 2-amino-2-methylpropanoate

Hot tags: 2-aminoisobutyric acid, China, manufacturers, suppliers, factory, wholesale, low price, high quality