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Picture of 2-Amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid

2-Amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid

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Origin: China

Cas No: 75802-84-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 75802-84-5 Formula: C10H11ClN2O3 Molecular Weight: 242.65900

    Description

    L-4-Chlorokynurenine (4-Cl-KYN; developmental code name AV-101) is an orally active small molecule prodrug candidate that in vivo produces a glycine binding site NMDA receptor antagonist. AV-101 is in clinical development by VistaGen Therapeutics. Inc. as a potential new generation, fast-acting antidepressant, and for other central nervous system (CNS) indications. The initial Phase 2 clinical study of AV-101 is expected to begin in 2015 and will be focused on treatment-resistant depression (TRD) and major depressive disorder (MDD).

    Basic Info

    Chemical Name 2-Amino-4-(2-amino-4-chlorophenyl)-4-oxobutanoic acid
    Synonyms

    4-Cl-KYN;
    4-Chloro-DL-kynurenine;
    4-Chlorokynurenine;

    CAS No. 75802-84-5
    Molecular Formula C10H11ClN2O3
    Molecular Weight 242.65900
    PSA 106.41000
    LogP 2.18840

    Properties

    Density 1.454g/cm3
    Boiling Point 516.3ºC at 760 mmHg
    Flash Point 266.1ºC
    Refractive Index 1.634

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