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2-Amino-1-(2,5-dimethoxyphenyl)ethanol

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Origin: China

Cas No: 3600-87-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 3600-87-1 Formula: C10H15NO3 Molecular Weight: 197.23100

Description

A metabolite of Midodrine. It induces alpha-adrenergic receptor stimulation of both arterial and venous systems without direct central nervous systme of cardiac effects.

Basic Info

Chemical Name	2-Amino-1-(2,5-dimethoxyphenyl)ethanol
Synonyms	ST 1059 (Desglymidodrine); 1-(2',5'-Dimethoxyphenyl)aminoethanol; (+/-)-2-amino-1-(2,5-dimethoxyphenyl)ethanol; 2-amino-1-(2,5-dimethoxyphenyl)ethan-1-ol; 1-(2',5'-dimethoxyphenyl)-2-aminoethanol; Midodrine Related Compound A; de-glymidodrine;
CAS No.	3600-87-1
Molecular Formula	C10H15NO3
Molecular Weight	197.23100
PSA	64.71000
LogP	1.39620

Properties

Boiling Point	364.3ºC at 760mmHg
Melting Point	146-150ºC dec.
Flash Point	174.1ºC
Refractive Index	1.542

Safety Info

HS Code	2922509090

Synthesis Route

2-(2,5-dimethoxyphenyl)-2-hydroxyacetonitrile→2-Amino-1-(2,5-dimethoxyphenyl)ethanol
2-(2,5-dimethoxyphenyl)-2-((trimethylsilyl)oxy)acetonitrile→2-Amino-1-(2,5-dimethoxyphenyl)ethanol
1,2-epoxy-1-(2,5-dimethoxyphenyl)ethane→2-Amino-1-(2,5-dimethoxyphenyl)ethanol

Precursor

2-Bromo-2,5-Dimethoxyacetophenone
1,2-epoxy-1-(2,5-dimethoxyphenyl)ethane
2,5-Dimethoxybenzaldehyde
2-(2,5-dimethoxyphenyl)-2-hydroxyacetonitrile

Downstream Product

2-chloro-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide

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