Home > Organofluorine Compounds> 2-(5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamine

2-(5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamine

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Origin: China

Cas No: 22120-36-1

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 22120-36-1 Formula: C12H15FN2 Molecular Weight: 206.25900

Description

5-Fluoro-N,N-dimethyltryptamine (5-fluoro-DMT) is a tryptamine derivative related to compounds such as 5-bromo-DMT and 5-MeO-DMT. Fluorination of psychedelic tryptamines either reduces or has little effect on 5-HT2A/C receptor affinity or intrinsic activity, although 6-fluoro-DET is inactive as a psychedelic despite acting as a 5-HT2A agonist (cf. lisuride), while 4-fluoro-5-methoxy-DMT is a much stronger agonist at 5-HT1A than 5-HT2A.

Basic Info

Chemical Name	2-(5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamine
Synonyms	N,N-Dimethyl-5-fluoro-1H-indole-3-ethanamine; 6-Fluoro-DMT; 5-Fluor-N,N-dimethyl-tryptamin; 5-Fluoro-DMT; 5-Fluoro-N,N-dimethyltryptamine;
CAS No.	22120-36-1
Molecular Formula	C12H15FN2
Molecular Weight	206.25900
PSA	19.03000
LogP	2.41110

Properties

Density	1.151g/cm3
Boiling Point	335.7ºC at 760mmHg
Flash Point	156.8ºC
Refractive Index	1.597
Vapor Pressure	0.000118mmHg at 25°C

Safety Info

HS Code	2933990090

Synthesis Route

5-fluoro-3-(2-hydroxyethyl)-1H-indole methanesulfonate+Dimethylamine→2-(5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamine
4,4-dimethoxy-N,N-dimethylbutan-1-amine+4-Fluorophenylhydrazine hydrochloride→2-(5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamine
Formaldehyde+5-Fluorotryptamine→2-(5-fluoro-1H-indol-3-yl)-N,N-dimethylethanamine

Precursor

Dimethylamine
4,4-dimethoxy-N,N-dimethylbutan-1-amine
Formaldehyde
4-Fluorophenylhydrazine hydrochloride

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