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2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate,2-hydroxyethyl(trimethyl)azanium

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Origin: China

Cas No: 856676-23-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

Property

CAS No.: 856676-23-8 Formula: C22H28ClNO5 Molecular Weight: 421.91400

Description

A new formulation of fenofibric acid, ABT-335, co-administered with statins.

Basic Info

Chemical Name	2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate,2-hydroxyethyl(trimethyl)azanium
Synonyms	UNII-4BMH7IZT98; ABT-335; Fenofibrate de choline; fenofibric acid choline salt; Choline fenofibrate;
CAS No.	856676-23-8
Molecular Formula	C22H28ClNO5
Molecular Weight	421.91400
PSA	86.66000
LogP	2.16320

Properties

Boiling Point	486.5ºC at 760 mmHg
Flash Point	248ºC

Synthesis Route

Ethyl 2-Bromoisobutyrate+4-Chloro-4'-hydroxybenzophenone→2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate,2-hydroxyethyl(trimethyl)azanium
fenofibric acid+choline chloride→2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate,2-hydroxyethyl(trimethyl)azanium
Isopropyl 2-bromo-2-methylpropanoate+4-Chloro-4'-hydroxybenzophenone→2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate,2-hydroxyethyl(trimethyl)azanium

Precursor

4-Chloro-4'-hydroxybenzophenone
2-Hydroxyethyltrimethylammonium Hydroxide
fenofibric acid
Ethyl 2-Bromoisobutyrate

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