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2-(2-phenylmethoxyphenyl)acetic acid

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Origin: China

Cas No: 22047-88-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 22047-88-7 Formula: C15H14O3 Molecular Weight: 242.27000

Description

2-Phenylmethoxybenzeneacetic Acid, is a novel O-substituted Hydroxyphenylacetic Acid derivatives, having aldose reductase inhibitory activities. It can also be used for the synthesis of Asperphenamate derivatives, having antitumor activity.

Basic Info

Chemical Name	2-(2-phenylmethoxyphenyl)acetic acid
Synonyms	2-hydroxyphenylacetic acid benzyl ether; O-Benzyloxyphenylacetic acid; 2-Benzyloxyphenylacetic acid;
CAS No.	22047-88-7
Molecular Formula	C15H14O3
Molecular Weight	242.27000
PSA	46.53000
LogP	2.89270

Properties

Appearance & Physical State	WHITE TO TAN SOLID, POWDER, CRYSTALS CRYSTALLINE POWDER AND/OR CHUNKS
Density	1.201 g/cm3
Boiling Point	406.9ºC at 760 mmHg
Melting Point	96-98ºC
Flash Point	153.2ºC
Refractive Index	1.595
Vapor Pressure	2.03E-07mmHg at 25°C

Safety Info

Safety Statements	S26-S36
RIDADR	UN 3077 9
Risk Statements	R36/37/38
Hazard Codes	Xn; Xi; N

Synthesis Route

o-benzyloxyphenyl-N-hydroxy-N-(p-dimethylamino)phenylacetamide→2-(2-phenylmethoxyphenyl)acetic acid+o-benzyloxyphenyl-N-(p-dimethylamino)phenylacetamide
benzyl bromide+(2-hydroxyphenyl)acetic acid→2-(2-phenylmethoxyphenyl)acetic acid
benzyl (2-benzyloxyphenyl)acetate→2-(2-phenylmethoxyphenyl)acetic acid

Precursor

benzyl (2-benzyloxyphenyl)acetate
benzyl bromide
(2-hydroxyphenyl)acetic acid
2-Benzyloxyphenylacetonitrile

Downstream Product

methyl 2-(2-phenylmethoxyphenyl)acetate

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