Главная > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> (1S,3S,4aR,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H- pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naph thalenyl (2S)-2-methylbutanoate

(1S,3S,4aR,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H- pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naph thalenyl (2S)-2-methylbutanoate

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начало: Китай

Кас Но: 77517-29-4

Спецификация: 99%наименьший

минимальный объем заказа: 1 /kg

снабженческая способность: 50 mt/month

опережающий период: OEM 7 дней, пятно 3 дня

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CAS No.: 77517-29-4 Formula: C24H38O5 Molecular Weight: 406.55600

Description

4a,5-Dihydro Lovastatin is an impurity in Lovastatin bulk drug.

Basic Info

Chemical Name	(1S,3S,4aR,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H- pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naph thalenyl (2S)-2-methylbutanoate
Synonyms
CAS No.	77517-29-4
Molecular Formula	C24H38O5
Molecular Weight	406.55600
PSA	72.83000
LogP	4.27540

Properties

Density	1.1g/cm3
Boiling Point	534.8ºC at 760 mmHg
Flash Point	174.5ºC
Refractive Index	1.52

Synthesis Route

(1S,2S,4aR,6S,8S,8aS,3'R,5'R,2''S)-methyl-1,2,4a,5,6,7,8,8a-octahydro-3',5'-dihydroxy-2,6-dimethyl-8-((2-methyl-1-oxobutyl)oxy)-1-naphthaleneheptanoate→(1S,3S,4aR,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H- pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naph thalenyl (2S)-2-methylbutanoate
methyl (1S,2S,4aR,6S,8S,8aS,3'R,2''S)-3'-(tert-butyldimethylsiloxy)-7'-[1,2,4a,5,6,7,8,8a-octahydro-2,6-dimethyl-8-[(2''-methylbutyryl)oxy]-1-naphthalenyl]-5'-oxohept-6'-enoate→(1S,3S,4aR,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H- pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naph thalenyl (2S)-2-methylbutanoate
(2α,4α,4aβ,5β,6β,8aα)-octahydro-5-(hydroxymethyl)-2,6-dimethylnaphthalen-4-ol→(1S,3S,4aR,7S,8S,8aR)-8-{2-[(2R,4R)-4-Hydroxy-6-oxotetrahydro-2H- pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naph thalenyl (2S)-2-methylbutanoate

Precursor

(1RS,2SR,6SR,8SR,8aRS)-1,2,3,5,6,7,8,8a-octahydro-2,6-dimethyl-1-ethynyl-8-hydroxynaphthalene
(2α,4α,4aβ,5β,6β,8aα)-octahydro-5-(hydroxymethyl)-2,6-dimethylnaphthalen-4-ol
methyl (1S,2S,4aR,6S,8S,8aS,3'R,2''S)-3'-(tert-butyldimethylsiloxy)-7'-[1,2,4a,5,6,7,8,8a-octahydro-2,6-dimethyl-8-[(2''-methylbutyryl)oxy]-1-naphthalenyl]-5'-oxohept-6'-enoate
(1RS,2SR,6SR,8SR,8aRS)-1,2,3,5,6,7,8,8a-octahydro-2,6-dimethyl-8-hydroxy-1-ethenylnaphthalene

Популярные теги: (1s,3s,4ar,7s,8s,8ar)-8-{2-[(2r,4r)-4-hydroxy-6-oxotetrahydro-2h- pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naph thalenyl (2s)-2-methylbutanoate, Китай, производитель, поставщик, фабрика, оптовая торговля, низкая цена, высокое качество