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Picture of (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride

(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride

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Origin: China

CasNo: 866783-13-3

specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Description
  • Quick Details

    CAS No.:
    866783-13-3
    Other Names:
    (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane HCL
    MF:
    C12H18ClNO2
    EINECS No.:
    866783-13-3
    Place of Origin:
    Shanghai, China
    Grade Standard:
    Agriculture Grade, Electron Grade, Food Grade, Industrial Grade, Medicine Grade, Reagent Grade
    Purity:
    99%
    Appearance:
    White Powder
    Application:
    medicine
    Brand Name:
    Terppon
    Model Number:
    10133
    color:
    white

    Packaging&Delivery

    Packaging Details
    in 25kg drum
    Port
    Shanghai
    Lead Time:
    1 week
  • Property

    CAS No.: 866783-13-3 Formula: C12H18ClNO2 Molecular Weight: 243.73000

    Description

    (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane is an intermediate used in preparation of Ivabradine which is a selective bradycardic agent with direct effect on the pacemaker If current of the sinoatrial node.

    Basic Info

    Chemical Name (1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride
    Synonyms

    1-[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]-N-methylmethanamine,hydrochloride;

    CAS No. 866783-13-3
    Molecular Formula C12H18ClNO2
    Molecular Weight 243.73000
    PSA 30.49000
    LogP 2.75580

    Properties

    Boiling Point 338.6ºC at 760 mmHg
    Flash Point 158.6ºC

    Safety Info

    HS Code 2942000000

    Synthesis Route

    1-[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]-N-methylmethanamine(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride
    (S)-3,4-dimethoxy-bicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid N-methyl-amide(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride
    4,5-Dimethoxy-1-benzocyclobutenecarbonitrile(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane hydrochloride

    Precursor

    1-[(7S)-3,4-dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]-N-methylmethanamine
    (S)-3,4-dimethoxy-bicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid N-methyl-amide
    4,5-Dimethoxy-1-benzocyclobutenecarbonitrile
    3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid

    Downstream Product

    Dehydro Ivabradine
    ivabradine hydrochloride
    ivabradine

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