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(1R)-2-chloro-1-pyridin-3-ylethanol

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Origin: China

Cas No: 173901-03-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 173901-03-6 Formula: C7H8ClNO Molecular Weight: 157.59800

    Description

    (R)-2-Chloro-1-(3-pyridyl)ethanol is used in the synthetic preparation of chiral amino(pyridinyl)ethanol via lipase-mediated kinetic resolution.

    Basic Info

    Chemical Name (1R)-2-chloro-1-pyridin-3-ylethanol
    Synonyms

    CAS No. 173901-03-6
    Molecular Formula C7H8ClNO
    Molecular Weight 157.59800
    PSA 33.12000
    LogP 1.35380

    Properties

    Density 1.259 g/cm3
    Boiling Point 299.5ºC at 760 mmHg
    Refractive Index 1.557
    Vapor Pressure 0.00053mmHg at 25°C

    Synthesis Route

    2-chloro-1-pyridin-3-ylethanone,hydrochloride→(1R)-2-chloro-1-pyridin-3-ylethanol
    2-chloro-1-pyridin-3-ylethanone→(1R)-2-chloro-1-pyridin-3-ylethanol
    2-chloro-1-pyridin-3-ylethanone→(S)-3-(1-hydroxy-2-chloroethyl)-pyridine+(1R)-2-chloro-1-pyridin-3-ylethanol

    Precursor

    1-pyridin-3-ylethanone
    2-chloro-1-pyridin-3-ylethanone
    2-chloro-1-pyridin-3-ylethanone,hydrochloride

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