Home > Aromatic Compounds> 1H-Pyrazole-1-carboxamidine hydrochloride

1H-Pyrazole-1-carboxamidine hydrochloride

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Origin: China

Cas No: 4023-02-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 4023-02-3 Formula: C4H7ClN4 Molecular Weight: 146.57800

Description

A stable and versatile reagent for the efficient and chemically specific guanylation of sterically unhindered primary and secondary aliphatic amines under mild conditions. Useful reagent in peptide synthesis.

Basic Info

Chemical Name	1H-Pyrazole-1-carboxamidine hydrochloride
Synonyms	Pyrazole-1-carboximidamide Hydrochloride; 1-Carbamimidoylpyrazole Hydrochloride; 1H-Pyrazole-1-carboxamidine monohydrochloride; PRAXADINE HYDROCHLORIDE; PYRAZOLE CARBOXAMIDINE HCL; 1-Pyrazolecarboxamidine Hydrochloride; 1-amidinopyrazole hydrochloride; 1H-pyrazole-1-carbamidine monohydrochloride; Pyrazole-1-carboxamidine Hydrochloride; 1-amidinopyrazole monohydrochloride; 1H-pyrazole-1-carboxamidine; PYRAZOLE-1-CARBOXAMIDINE; N-GUANYLPYRAZOLE; 1H-Pyrazole-1-carboximidamide hydrochloride; AMIDINOPYRAZOLE HCL; amidinopyrazole hydrochloride; 1H-Pyrazole-1-Carboxamidine Hydrochloride; Zanamivir Intermediate 1; 1H-Pyrazole-carboxamidineHCl; Praxadine;
CAS No.	4023-02-3
Molecular Formula	C4H7ClN4
Molecular Weight	146.57800
PSA	67.69000
LogP	1.22670

Properties

Appearance & Physical State	white to light yellow crystals or crystalline
Density	2.2 g/cm3
Boiling Point	891.5ºC at 760 mmHg。产品描述安全性：
Melting Point	167-170ºC
Flash Point	493ºC
Refractive Index	1.724
Vapor Pressure	0.00111mmHg at 25°C

Safety Info

Safety Statements	S26-S37/39
HS Code	2933199090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi
Caution Statement	P273; P280; P305 + P351 + P338
Signal Word	Danger
Hazard Declaration	H302; H317; H318; H373; H412
Symbol	GHS05, GHS07, GHS08

Synthesis Route

1H-pyrazole+cyanamide→1H-Pyrazole-1-carboxamidine hydrochloride
1,1,3,3-Tetramethoxypropane+Aminoguanidine bicarbonate→1H-Pyrazole-1-carboxamidine hydrochloride
cyanamide+1H-pyrazole,hydrochloride→1H-Pyrazole-1-carboxamidine hydrochloride

Precursor

1H-pyrazole,hydrochloride
1,1,3,3-Tetramethoxypropane
1H-pyrazole
cyanamide

Downstream Product

2-hexylguanidine
diaminomethylidene(hexadecyl)azanium,chloride
2-(diaminomethylideneamino)acetic acid,hydrochloride
2-decylguanidine,hydrochloride

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