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16β-hydroxyestradiol

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Origin: China

Cas No: 547-81-9

Specification: 99%min

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 547-81-9 Formula: C18H24O3 Molecular Weight: 288.38100

    Description

    Epiestriol (INN) (brand names Actriol, Arcagynil, Klimadoral), or epioestriol (BAN), also known as 16β-epiestriol or simply 16-epiestriol as well as 16β-hydroxy-17β-estradiol, is an endogenous, steroidal, weak estrogen, and the 16-epimer of estriol (which is 16α-hydroxy-17β-estradiol). Epiestriol is (or has previously been) used clinically in the treatment of acne. In addition to its estrogenic actions, epiestriol has been found to possess significant anti-inflammatory properties without glycogenic activity or immunosuppressive effects, an interesting finding that is in contrast to conventional anti-inflammatory steroids like hydrocortisone (a glucocorticoid).

    Basic Info

    Chemical Name 16β-hydroxyestradiol
    Synonyms

    16beta-hydroxyestradiol;
    Actriol;
    Epiestriol;
    EPIESTRIOL,16;
    16-EPISTRIOL;
    Estriol (3,16.β.,17.β.);
    16-Epiestratriol;
    Epioestriol;
    16-EPIESTRIOL;
    Estra-1,3,5(10)-triene-3,16,17-triol, (16β,17β)-;
    16b,17b-Estriol;
    16-epioestriol;

    CAS No. 547-81-9
    Molecular Formula C18H24O3
    Molecular Weight 288.38100
    PSA 60.69000
    LogP 2.58000

    Properties

    Density 1.255g/cm3
    Boiling Point 469ºC at 760 mmHg
    Melting Point 289-291ºC
    Flash Point 220.8ºC
    Refractive Index 1.624
    Storage Condition -20ºC Freezer

    Safety Info

    WGK Germany 3

    Synthesis Route

    Ethanol+16-Oxo-17beta-estradiolestriol+16β-hydroxyestradiol

    Downstream Product

    1,3,5(10)-ESTRATRIEN-3,16-β, 17-β-TRIOL 3-METHYL ETHER

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