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1,4-Bis(2-hydroxyethyl)piperazine

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Origin: China

Cas No: 122-96-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 122-96-3 Formula: C8H18N2O2 Molecular Weight: 174.24100

Basic Info

Chemical Name	1,4-Bis(2-hydroxyethyl)piperazine
Synonyms	2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanol; 1,4-Piperazinediethanol; 2,2'-(Piperazine-1,4-diyl)diethanol;
CAS No.	122-96-3
Molecular Formula	C8H18N2O2
Molecular Weight	174.24100
PSA	46.94000
LogP	-1.53560

Properties

Appearance & Physical State	white crystalline powder
Density	1.097 g/cm3
Boiling Point	215 - 220 at 50 mmHg
Melting Point	133 - 136ºC
Flash Point	166.2ºC
Vapor Pressure	7.58E-05mmHg at 25°C

Safety Info

RTECS	TL3675000
Safety Statements	37/39-26
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

2-(1-oxa-4-azaspiro[4.5]decan-4-yl)ethanol→1,4-Bis(2-hydroxyethyl)piperazine+Cyclohexanone
ethanolamine→N-(2-Hydroxyethyl)piperazine+1,4-Bis(2-hydroxyethyl)piperazine
oxirane+piperazine→N-(2-Hydroxyethyl)piperazine+1,4-Bis(2-hydroxyethyl)piperazine

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Administration onto the skin	Open irritation test	Rodent - rabbit	10 mg/24H	-
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	3730 uL/kg	1.Details of toxic effects not reported other than lethal dose value
Administration onto the skin	LD50 - Lethal dose, 50 percent kill	Rodent - rabbit	>10 mL/kg	1.Details of toxic effects not reported other than lethal dose value

Precursor

oxirane
Diethanolamine
3-(2-hydroxyethyl)-1,3-oxazolidin-2-one
piperazine

Downstream Product

Triethylenediamine
Ethanamine, 1,1,2,2,2-pentafluoro-N-(1,1,2,2,2-pentafluoroethyl)-N-(trifluoromethyl)-
perfluoro(4-methylpiperazin-1-ylacetyl fluoride)
Acetyl fluoride, [bis(pentafluoroethyl)amino]difluoro-

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