Início > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> (11E)-11-[3-(dimethylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol

(11E)-11-[3-(dimethylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol

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Origem: China

Cas No: 64520-05-4

Especificação: 99%Min

Quantidade de ordem min: 1 /kg

Capacidade de fornecimento: 80 mt/month

Tempo de espera: 7 dias para OEM, 3 dias para produtos prontos

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CAS No.: 64520-05-4 Formula: C20H23NO Molecular Weight: 293.40300

Basic Info

Chemical Name	(11E)-11-[3-(dimethylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol
Synonyms	5H-Dibenzo(a,d)cyclohepten-10-ol,5-(3-(dimethylamino)propylidene)-10,11-dihydro-,(E); Amitriptyline metabolite,( inverted exclamation markA)-E-10-hydroxylated; ( inverted exclamation markA)-(E)-5-[3-(Dimethylamino)propylidene]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol;
CAS No.	64520-05-4
Molecular Formula	C20H23NO
Molecular Weight	293.40300
PSA	23.47000
LogP	3.65950

Properties

Density	1.151g/cm3
Boiling Point	453.3ºC at 760mmHg
Flash Point	225.4ºC
Refractive Index	1.651

Synthesis Route

amitriptyline→nortriptyline+10-Hydroxyamitriptyline
N,Ndimethyl-3-(10,11-dihydro-10-oxo-5H-dibenzo[a,d]cycloheptene)-Δ5,γ-propylamine→(11E)-11-[3-(dimethylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol
N,N-dimethyl-3-(10-(piperidin-1-yl)-5H-dibenzo[a,d][7]annulen-5-ylidene)propan-1-amine→(11E)-11-[3-(dimethylamino)propylidene]-5,6-dihydrodibenzo[2,1-b:2',1'-f][7]annulen-5-ol

Precursor

N,Ndimethyl-3-(10,11-dihydro-10-oxo-5H-dibenzo[a,d]cycloheptene)-Δ5,γ-propylamine
3-(10-bromo-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine
N,N-dimethyl-3-(10-(piperidin-1-yl)-5H-dibenzo[a,d][7]annulen-5-ylidene)propan-1-amine
amitriptyline

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