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(1-hydroxy-2,2,5,5-tetramethylpyrrolidin-3-yl)methanol

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Origin: China

Cas No: 27298-75-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 27298-75-5 Formula: C9H19NO2 Molecular Weight: 173.25300

Description

A reactive spin label. Hydroxytetramethylpiperidine derivatives and analogs for use in drug resistance reversal in neoplastic diseases.

Basic Info

Chemical Name	(1-hydroxy-2,2,5,5-tetramethylpyrrolidin-3-yl)methanol
Synonyms	Hydroxymethyl-proxyl; 3-Hydroxymethyl-2,2,5,5-tetramethylpyrrolidine-1-oxyl; Proxmethol; 1-oxyl-3-hydroxymethyl-2,2,5,5-tetramethylpyrrolidine; HM-PROXYL; (2,2,5,5-tetramethylpyrrolidin-1-oxyl-3-yl)methanol; 3-(HYDROXYMETHYL)-1-OXY-2,2,5,5-TETRAMETHYLPYRROLIDINE; 3-hydroxymethyl-2,2,5,5-tetramethyl-pyrrolidinyl-1-oxy; 3-hydroxymethylproxyl; 3-Hydroxymethyl-2,2,5,5-tetramethylpyrrolidin-1-oxyl;
CAS No.	27298-75-5
Molecular Formula	C9H19NO2
Molecular Weight	173.25300
PSA	43.70000
LogP	1.18490

Properties

Density	1.006g/cm3
Boiling Point	257.302ºC at 760 mmHg
Flash Point	108.361ºC
Refractive Index	1.475
Vapor Pressure	0.002mmHg at 25°C

Synthesis Route

→(1-hydroxy-2,2,5,5-tetramethylpyrrolidin-3-yl)methanol+3-Hydroxymethyl-(1-oxy-2,2,5,5-tetramethylpyrroline)
→(1-hydroxy-2,2,5,5-tetramethylpyrrolidin-3-yl)methanol
2,2,5,5-TETRAMETHYL-3-PYRROLIN-1-OXYL-3-CARBOXYLIC ACID→(1-hydroxy-2,2,5,5-tetramethylpyrrolidin-3-yl)methanol

Precursor

2,2,5,5-TETRAMETHYL-3-PYRROLIN-1-OXYL-3-CARBOXYLIC ACID

Downstream Product

(1-λ<sup>1</sup>-oxidanyl-2,2,5,5-tetramethylpyrrolidin-3-yl)methanamine
1-hydroxy-3-(isothiocyanatomethyl)-2,2,5,5-tetramethylpyrrolidine

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