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1-(Cbz-Amino)Cyclopropanecarboxylic Acid

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Origin: China

Cas No: 84677-06-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 84677-06-5 Formula: C12H13NO4 Molecular Weight: 235.23600

Basic Info

Chemical Name	1-(Cbz-Amino)Cyclopropanecarboxylic Acid
Synonyms	1-(phenylmethoxycarbonylamino)cyclopropane-1-carboxylic acid;
CAS No.	84677-06-5
Molecular Formula	C12H13NO4
Molecular Weight	235.23600
PSA	75.63000
LogP	1.92090

Properties

Density	1.33g/cm3
Boiling Point	449ºC at 760 mmHg
Flash Point	225.4ºC
Refractive Index	1.593
Storage Condition	-20ºC

Safety Info

Safety Statements	S26-S36
HS Code	2924299090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi

Synthesis Route

N-(Benzyloxycarbonyloxy)succinimide+1-Aminocyclopropanecarboxylic acid hydrochloride→1-(Cbz-Amino)Cyclopropanecarboxylic Acid
N-(Benzyloxycarbonyloxy)succinimide+1-aminocyclopropanecarboxylic acid→1-(Cbz-Amino)Cyclopropanecarboxylic Acid
benzyl 1-(methoxycarbonyl)cyclopropylcarbamate→1-(Cbz-Amino)Cyclopropanecarboxylic Acid

Precursor

methyl Nα-benzyloxycarbonylamino-γ-bromobutyrate
N-(Benzyloxycarbonyloxy)succinimide
benzyl 1-(methoxycarbonyl)cyclopropylcarbamate
1-Aminocyclopropanecarboxylic acid hydrochloride

Downstream Product

4,7-Diazaspiro[2.5]octane-5,8-dione
benzyl N-(1-carbamothioylcyclopropyl)carbamate
Benzyl (1-(hydroxymethyl)cyclopropyl)carbamate
1-aminocyclopropanecarboxylic acid

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