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1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone

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Origin: China

Cas No: 43229-01-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 43229-01-2 Formula: C15H12BrNO4 Molecular Weight: 350.16400

Description

1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone, can be used as an intermediate in the synthesis of Arformoterol Tartrate, which is a derivative of Arformoterol, a long acting beta-adrenoceptor agonist drug indicated for the treatment of chronic obstructive pulmonary disease (COPD).

Basic Info

Chemical Name	1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone
Synonyms	2-bromo-1-(3-nitro-4-phenylmethoxyphenyl)ethanone;
CAS No.	43229-01-2
Molecular Formula	C15H12BrNO4
Molecular Weight	350.16400
PSA	72.12000
LogP	4.27460

Properties

Density	1.517g/cm3
Boiling Point	465.2ºC at 760mmHg
Refractive Index	1.627

Safety Info

HS Code	2914700090

Synthesis Route

1-(4-(Benzyloxy)-3-nitrophenyl)ethanone→1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone
4'-Hydroxy-3'-nitroacetophenone→1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone
4'-hydroxyacetophenone→1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone

Precursor

4'-hydroxyacetophenone
benzyl chloride
1-(4-(Benzyloxy)-3-nitrophenyl)ethanone
benzyl bromide

Downstream Product

2-(3-nitro-4-phenylmethoxyphenyl)oxirane
(2R)-2-(3-nitro-4-phenylmethoxyphenyl)oxirane
(S)-4-benzyloxy-3-nitrostyrene oxide
N-[5-[(1R)-2-bromo-1-hydroxyethyl]-2-phenylmethoxyphenyl]formamide

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