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1-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine

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Origin: China

Cas No: 61337-88-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 61337-88-0 Formula: C17H18N4 Molecular Weight: 278.35200

Description

Used in the preparation of Mirtazapine impurities.

Basic Info

Chemical Name	1-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine
Synonyms	2-(4-methyl-2-phenylpiperazin-1-yl)pyridine-3-carbonitrile;
CAS No.	61337-88-0
Molecular Formula	C17H18N4
Molecular Weight	278.35200
PSA	43.16000
LogP	2.44928

Safety Info

HS Code	2933599090

Synthesis Route

2-Chloro-3-cyanopyridine+1-Methyl-3-phenylpiperazine→2-(4-Methyl-2-phenylpiperazin-1-yl)nicotinic acid+1-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine
2-Chloro-3-cyanopyridine+1-Methyl-3-phenylpiperazine→1-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine
2-Chloro-3-cyanopyridine+nonan-2-one→1-(3-Cyano-2-pyridyl)-4-methyl-2-phenylpiperazine

Precursor

nonan-2-one
1-methyl-3-phenylpiperazine hydrochloride
1-Methyl-3-phenylpiperazine
2-Chloro-3-cyanopyridine

Downstream Product

Mirtazapine
2-(4-Methyl-2-phenylpiperazin-1-yl)nicotinic acid
2-(4-Methyl-2-phenyl-1-piperazinyl)-3-pyridinemethanol

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