Home > Organosilicon Compounds> 1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione

1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione

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Origin: China

Cas No: 159140-63-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 159140-63-3 Formula: C15H25IN2O5Si Molecular Weight: 468.35900

Basic Info

Chemical Name	1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
Synonyms	Uridine,2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-5-iodo; 3'-O-(tert-butyldimethylsilyl)-5-iodo-2'-deoxyuridine;
CAS No.	159140-63-3
Molecular Formula	C15H25IN2O5Si
Molecular Weight	468.35900
PSA	93.81000
LogP	2.22370

Synthesis Route

2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine→1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
5-iodo-2'-deoxyuridine→1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione

Precursor

2'-deoxy-3',5'-bis(O-tert-butyldimethylsilyl)-5-iodouridine
5-iodo-2'-deoxyuridine

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