Home > Chiral Compounds> 1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

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Origin: China

Cas No: 7057-27-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

Property

CAS No.: 7057-27-4 Formula: C9H12N2O5 Molecular Weight: 228.20200

Description

A potential anti-cancer and anti-viral agents.

Basic Info

Chemical Name	1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Synonyms	Uridine,3'-deoxy; 3'-deoxy-uridine; 3'-Desoxy-uridin;
CAS No.	7057-27-4
Molecular Formula	C9H12N2O5
Molecular Weight	228.20200
PSA	104.55000
LogP	-1.82270

Properties

Melting Point	176-177°C

Synthesis Route

2',5'-di-O-acetyl-3'-deoxyuridine→1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
1-(3-S-Benzyl-3-thio-β-D-xylofuranosyl)uracil→1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
3'-deoxy-5'-O-trityluridine→1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

Precursor

2',5'-di-O-acetyl-3'-deoxyuridine
uridine
3'-deoxy-5'-O-trityluridine
1-(3-S-Benzyl-3-thio-β-D-xylofuranosyl)uracil

Downstream Product

N-[1-[(2R,3R,5S)-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
N-[1-[(2R,3R,5S)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-hydroxyoxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide
3'-DEOXYCYTIDINE
[[(2S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-4-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] phosphono hydrogen phosphate

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