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Home > All categories> Biochemicals and Pharmaceutical Chemicals> Pharmaceutical Impurities> 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride
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1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride

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Origin: China

Cas No: 70918-74-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 70918-74-0 Formula: C13H17ClN2O3 Molecular Weight: 284.73900

    Description

    1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazine Monohydrochloride is an impurity of Doxazosin, a selective α1-adrenoceptor antagonist. Doxazosin relaxes smooth muscles of the prostate.

    Basic Info

    Chemical Name 1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride
    Synonyms

    2,3-dihydro-1,4-benzodioxin-3-yl(piperazin-1-yl)methanone,hydrochloride;

    CAS No. 70918-74-0
    Molecular Formula C13H17ClN2O3
    Molecular Weight 284.73900
    PSA 50.80000
    LogP 1.32690

    Properties

    Appearance & Physical State white or white like crystalline powder
    Boiling Point 437.2ºC at 760 mmHg
    Melting Point 105-108ºC
    Flash Point 218.2ºC

    Safety Info

    Safety Statements S45-S53-S61
    HS Code 2934999090
    Risk Statements R23/24/25; R48/22; R51/53
    Hazard Codes T; N

    Synthesis Route

    piperazine+2,3-Dihydro-1,4-benzodioxine-2-carbonyl chloride→1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride
    piperazine+Ethyl 1,4-Benzodioxane-2-carboxylate→1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine hydrochloride

    Precursor

    piperazine
    2,3-Dihydro-1,4-benzodioxine-2-carbonyl chloride
    Ethyl 1,4-Benzodioxane-2-carboxylate

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