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1-[2-Amino-1-(4-benzyloxyphenyl)-ethyl]-cyclohexanol

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Origin: China

Cas No: 93413-61-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 93413-61-7 Formula: C23H31NO2 Molecular Weight: 353.49800

Description

1-(1-(4-(Benzyloxy)phenyl)-2-(dimethylamino)ethyl)cyclohexanol is a reactant used in the synthesis of O-desmethylvenlafaxine succinate.

Basic Info

Chemical Name	1-[2-Amino-1-(4-benzyloxyphenyl)-ethyl]-cyclohexanol
Synonyms	O-benzyl desvenlafaxine;
CAS No.	93413-61-7
Molecular Formula	C23H31NO2
Molecular Weight	353.49800
PSA	32.70000
LogP	4.60600

Properties

Density	1.096
Boiling Point	493.9ºC at 760 mmHg
Flash Point	252.5ºC
Refractive Index	1.578

Safety Info

HS Code	2922509090

Synthesis Route

1-[(4-benzyloxyphenyl)dimethylaminocarbonylmethyl]cyclohexanol→1-[2-Amino-1-(4-benzyloxyphenyl)-ethyl]-cyclohexanol
Formaldehyde+1-(2-Amino-1-(4-(benzyloxy)phenyl)ethyl)cyclohexanol→1-[2-Amino-1-(4-benzyloxyphenyl)-ethyl]-cyclohexanol
1,5-Dibromopentane+2-(4-benzyloxy-phenyl)-3-dimethylamino-propionic acid methyl ester→1-[2-Amino-1-(4-benzyloxyphenyl)-ethyl]-cyclohexanol

Precursor

1-[(4-benzyloxyphenyl)dimethylaminocarbonylmethyl]cyclohexanol
Formaldehyde
2-(4-benzyloxy-phenyl)-3-dimethylamino-propionic acid methyl ester
1,5-Dibromopentane

Downstream Product

O-desmethylvenlafaxine

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