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(-)-2-Amino-6-propionamido-tetrahydrobenzothiazole

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Origin: China

Cas No: 106006-84-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 106006-84-2 Formula: C10H15N3OS Molecular Weight: 225.31100

Description

A pramipexole intermediate.

Basic Info

Chemical Name	(-)-2-Amino-6-propionamido-tetrahydrobenzothiazole
Synonyms	(6S)-2-Amino-6-propionamidotetrahydrobenzothiazole; (S)-N-(2-Amino-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl)propionamide;
CAS No.	106006-84-2
Molecular Formula	C10H15N3OS
Molecular Weight	225.31100
PSA	96.25000
LogP	2.08090

Properties

Appearance & Physical State	off-white solid
Density	1.26g/cm3
Boiling Point	502.9ºC at 760mmHg
Melting Point	187-188ºC
Flash Point	257.9ºC
Refractive Index	1.596
Vapor Pressure	3.06E-10mmHg at 25°C

Safety Info

HS Code	2934999090

Synthesis Route

N-(2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)propanamide→N-[(6R)-2-amino-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl]propanamide+(-)-2-Amino-6-propionamido-tetrahydrobenzothiazole
Propionic anhydride+(S)-N-Despropyl Pramipexole→(-)-2-Amino-6-propionamido-tetrahydrobenzothiazole
4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine→(-)-2-Amino-6-propionamido-tetrahydrobenzothiazole

Precursor

N-(4-Oxocyclohexyl)acetamide
(S)-N-Despropyl Pramipexole
4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
Propionic anhydride

Downstream Product

pramipexole
pramipexole hydrochloride anhydrous

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