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Home > Chiral Compounds> Zanamivir Azide Triacetate Methyl Ester
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Zanamivir Azide Triacetate Methyl Ester

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Origin: China

Cas No: 130525-58-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 130525-58-5 Formula: C18H24N4O10 Molecular Weight: 456.40400

    Description

    An intermediate used in the preparation of Zanamivir derivatives.

    Basic Info

    Chemical Name Zanamivir Azide Triacetate Methyl Ester
    Synonyms

    D-GLYCERO-D-GALACTO-NON-2-ENONIC ACID;

    CAS No. 130525-58-5
    Molecular Formula C18H24N4O10
    Molecular Weight 456.40400
    PSA 193.28000
    LogP -0.10414

    Properties

    Appearance & Physical State Off-white solid

    Synthesis Route

    methyl (3aR,4R,7aR)-2-methyl-4-[(1R,2R)-1,2,3-triacetyloxypropyl]-4,7a-dihydro-3aH-pyrano[3,4-d][1,3]oxazole-6-carboxylate→Zanamivir Azide Triacetate Methyl Ester
    →Zanamivir Azide Triacetate Methyl Ester
    methyl (5-acetamido-7,8,9-tri-O-acetyl-4-azido-2-chloro-3,4,5-trideoxy-β-D-glycerol-D-galacto-2-nonulopyranosid)onate→Zanamivir Azide Triacetate Methyl Ester

    Precursor

    methyl (3aR,4R,7aR)-2-methyl-4-[(1R,2R)-1,2,3-triacetyloxypropyl]-4,7a-dihydro-3aH-pyrano[3,4-d][1,3]oxazole-6-carboxylate
    N-{(R)-1-[(S)-Hydroxy-((4R,5R,4'R)-2,2,2',2'-tetramethyl-[4,4']bi[[1,3]dioxolanyl]-5-yl)-methyl]-but-3-enyl}-acetamide
    methyl (5-acetamido-7,8,9-tri-O-acetyl-4-azido-2-chloro-3,4,5-trideoxy-β-D-glycerol-D-galacto-2-nonulopyranosid)onate
    Methyl 5-acetamido-7,8,9-tri-O-acetyl-2,6-anhydro-3,5-dideoxy-D-glycero-D-talo-non-2-enonate

    Downstream Product

    methyl (2R,3R,4S)-3-acetamido-4-(cyanoamino)-2-[(1R,2R)-1,2,3-triacetyloxypropyl]-3,4-dihydro-2H-pyran-6-carboxylate
    4-a-Amino-N-acetyl-2-deoxy-2,3-didehydro-D-neuraminate
    zanamivir
    Zanamivir

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