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tyramine

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Origin: China

Cas No: 51-67-2

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Quick Details

    CAS No.:
    51-67-2
    Other Names:
    L-Tyramine
    MF:
    C8H11NO
    EINECS No.:
    51-67-2
    Place of Origin:
    China
    Type:
    Agrochemical Intermediates, Dyestuff Intermediates, Flavor & Fragrance Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
    Purity:
    ≥99%
    Brand Name:
    FinerChem
    Model Number:
    51-67-2
    Application:
    Organic synthesis
    Appearance:
    White powder
    Product name:
    Tyramine
    CAS:
    51-67-2
    Assay:
    99.0 %min
    Molecular Weight:
    137.18

    Packaging&Delivery

    Packaging Details
    Aluminum foil bag for within 10kg
    Fiber drum for 10kg and more
    Port
    SHANGHAI, BEIJING, QINGDAO, SHENZHEN, TIANJIN
    Lead Time:
    Quantity(Kilograms)1 - 500>500
    Est. Time(days)4To be negotiated

    Products Description

    Product Name
    Tyramine
    CAS No.
    51-67-2
    Appearance
    White powder
    Assay
    ≥99%
    Capacity
    200mt/year
    Min.packing
    1gram
    Application
    For organic synthesis; intermediates of bezafibrate
    Standard
    Export 
    Brand
    Finerchem 


    More information

    Synonyms: 2-(p-Hydroxyphenyl)ethylamine 
                         4-(2-Aminoethyl)phenol 
                         4-Hydroxyphenylethylamine 
                          L-Tyramine 
                          Tyrosamine 
    Molecular Formula: C8H11NO 
    Molecular Weight: 137.18 
    CAS Registry Number: 51-67-2 
    EINECS: 200-115-8 
    FEMA: 4215 
    Melting point: 155-163 ºC 
    Boiling point: 175-181 ºC (8 mmHg) 
    Water solubility: 1g/95mL (15 ºC)

  • Property

    CAS No.: 51-67-2 Formula: C8H11NO Molecular Weight: 137.17900

    Description

    Tyramine, also known by several other names, is a naturally occurring monoamine and trace amine derived from the amino acid tyrosine. Tyramine acts as a catecholamine releasing agent. Notably, it is unable to cross the blood-brain barrier, resulting in only non-psychoactive peripheral sympathomimetic effects. A hypertensive crisis can result, however, from ingestion of tyramine-rich foods in conjunction with monoamine oxidase inhibitors (MAOIs).

    Basic Info

    Chemical Name tyramine
    Synonyms

    4-(2-aminoethyl)-pheno;
    Uteramine;
    Tyramin;
    p-Tyramine;
    4-Hydroxyphenethylamine;
    Systogene;
    Tyrosamine;
    Phenol, 4-(2-aminoethyl)-;
    2-(4-Hydroxyphenyl)ethylamine;
    Tocosine;
    4-(2-Aminoethyl)phenol;
    4-hydroxy-phenethylamine;

    CAS No. 51-67-2
    Molecular Formula C8H11NO
    Molecular Weight 137.17900
    PSA 46.25000
    LogP 1.59370

    Properties

    Appearance & Physical State yellow to brown crystals
    Density 1.103g/cm3
    Boiling Point 175-181ºC (8 mmHg)
    Melting Point 155-163ºC
    Flash Point 165ºC
    Water Solubility 1g/95mL (15 ºC)
    Stability Stable. Incompatible with strong acids, strong oxidizing agents.
    Storage Condition Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

    Safety Info

    RTECS SJ5950000
    Safety Statements S26-S37/39
    HS Code 2922299090
    WGK Germany 3
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    L-Tyrosine→tyramine
    (4-Hydroxyphenyl)acetaldehyd-dimethylhydrazon→tyramine
    N,N'-Disuccinimidyl carbonate→tyramine

    GC Analysis

    Column type Active phase Temperature (°C) Retention Index (I) Temperature Control Method
    Packed SE-30 - 1405. custom temperature program
    Packed SE-30 - 1430. temperature ramp
    Capillary HP-5MS - 1660.9 custom temperature program
    Other Methyl Silicone - 1436. custom temperature program

    Toxicity

    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intraperitoneal LDLo - Lowest published lethal dose Rodent - mouse 800 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Subcutaneous LDLo - Lowest published lethal dose Rodent - mouse 225 mg/kg 1.Details of toxic effects not reported other than lethal dose value
    Intravenous LD50 - Lethal dose, 50 percent kill Rodent - mouse 229 mg/kg 1.Behavioral-changes in motor activity (specific assay)

    Precursor

    (4-Hydroxyphenyl)acetaldehyd-dimethylhydrazon
    N,N'-Disuccinimidyl carbonate
    tyramine-DIC
    (4-hydroxyphenyl)acetonitrile

    Downstream Product

    [4-(2-acetamidoethyl)phenyl] acetate
    4-(2-aminoethyl)-phenyl acetate
    N-[2-(4-hydroxyphenyl)ethyl]acetamide
    1,2,3,4-tetrahydroisoquinolin-7-ol

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