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tert-butyl (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxypropanoate

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Origin: China

Cas No: 110797-35-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 110797-35-8 Formula: C22H25NO5 Molecular Weight: 383.43800

Basic Info

Chemical Name	tert-butyl (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxypropanoate
Synonyms	(S)-N-(fluoren-9-ylmethoxycarbonyl)serine tert-butyl ester; Fmoc-serine tert-butyl ester; NALPHA-FMOC-L-SERINE TERT-BUTYL ESTER; Nα-[(9H-Fluoren-9-ylMethoxy)carbonyl]-L-serine tert-Butyl Ester; (S)-tert-butyl 2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-3-hydroxypropanoate; Fmoc-Ser(OH)-O-t-Bu; Nalpha-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-serine tert-Butyl Ester; Fmoc-Ser-OtBu; Fmoc-L-Ser-O-tBu; N-Fmoc-serine-OtBu;
CAS No.	110797-35-8
Molecular Formula	C22H25NO5
Molecular Weight	383.43800
PSA	84.86000
LogP	3.61860

Properties

Density	1.217g/cm3
Boiling Point	588.356ºC at 760 mmHg
Melting Point	127ºC
Flash Point	309.627ºC
Storage Condition	Refrigerator
Vapor Pressure	0mmHg at 25°C

Safety Info

HS Code	2924299090

Synthesis Route

tert-Butyl 2,2,2-trichloroacetimidate+Fmoc-L-Serine→tert-butyl (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxypropanoate
(S)-tert-butyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(trityloxy)propanoate→tert-butyl (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxypropanoate
Fmoc-L-Serine+tert-butanol→tert-butyl (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-hydroxypropanoate

Precursor

(S)-tert-butyl 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(trityloxy)propanoate
Fmoc-L-Serine
tert-butanol
tert-Butyl 2,2,2-trichloroacetimidate

Downstream Product

tert-butyl (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-3-iodopropanoate

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