Home > Chiral Compounds> (R)-tert-Butyl 2-methylpyrrolidine-1-carboxylate

(R)-tert-Butyl 2-methylpyrrolidine-1-carboxylate

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Origin: China

Cas No: 157007-54-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 157007-54-0 Formula: C10H19NO2 Molecular Weight: 185.26300

Basic Info

Chemical Name	(R)-tert-Butyl 2-methylpyrrolidine-1-carboxylate
Synonyms	(R)-1-Boc-2-methylpyrrolidine; (R)-(-)-1-Boc-2-methylpyrrolidine; tert-butyl (2R)-2-methylpyrrolidine-1-carboxylate;
CAS No.	157007-54-0
Molecular Formula	C10H19NO2
Molecular Weight	185.26300
PSA	29.54000
LogP	2.34370

Properties

Density	0.99g/cm3
Boiling Point	234ºC at 760mmHg
Flash Point	95.3ºC
Refractive Index	n20/D 1.447

Safety Info

Safety Statements	S26
Risk Statements	R36/37/38
Hazard Codes	C; F; Xi

Synthesis Route

1-Boc-Pyrrolidine+dimethyl sulfate→tert-butyl (2S)-2-methylpyrrolidine-1-carboxylate+(R)-tert-Butyl 2-methylpyrrolidine-1-carboxylate
tert-butoxycarbonyl anhydride→tert-butyl (2S)-2-methylpyrrolidine-1-carboxylate+(R)-tert-Butyl 2-methylpyrrolidine-1-carboxylate
1-Boc-Pyrrolidine+iodomethane→tert-butyl (2S)-2-methylpyrrolidine-1-carboxylate+(R)-tert-Butyl 2-methylpyrrolidine-1-carboxylate

Precursor

tert-butyl (2S)-2-(iodomethyl)pyrrolidine-1-carboxylate
N-Boc-O-methanesulfonylprolinol
N-Boc-L-Prolinol
dimethyl sulfate

Downstream Product

(2R)-1-but-3-ynyl-2-methylpyrrolidine
(R)-4-(2-(2-(2-Methylpyrrolidin-1-yl)Ethyl)benzofuran-5-yl)benzonitrile

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