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Home > Chiral Compounds> (R)-(-)-α-Methylhistamine dihydrobromide,(R)-(-)-α-Methyl-1H-imidazole-4-ethanaminedihydrobromide
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(R)-(-)-α-Methylhistamine dihydrobromide,(R)-(-)-α-Methyl-1H-imidazole-4-ethanaminedihydrobromide

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Origin: China

Cas No: 75614-87-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 75614-87-8 Formula: C6H13Cl2N3 Molecular Weight: 198.09400

    Description

    α-Methylhistamine is a histamine agonist selective for the receptor subtype H3. It causes lowering of blood pressure and a decrease of heart rate in animal models.

    Basic Info

    Chemical Name (R)-(-)-α-Methylhistamine dihydrobromide,(R)-(-)-α-Methyl-1H-imidazole-4-ethanaminedihydrobromide
    Synonyms

    CAS No. 75614-87-8
    Molecular Formula C6H13Cl2N3
    Molecular Weight 198.09400
    PSA 54.70000
    LogP 2.60370

    Properties

    Density 1.094 g/cm3
    Boiling Point 320.6ºC at 760 mmHg
    Flash Point 173.7ºC
    Refractive Index 1.55
    Storage Condition Desiccate at RT

    Safety Info

    Safety Statements S26; S36
    Risk Statements R36/37/38
    Hazard Codes Xi

    Synthesis Route

    (S)-(+)-4-(2-amino-3-chloropropyl)-imidazole dihydrochloride→(R)-(-)-α-Methylhistamine dihydrobromide,(R)-(-)-α-Methyl-1H-imidazole-4-ethanaminedihydrobromide
    L-histidinol→(R)-(-)-α-Methylhistamine dihydrobromide,(R)-(-)-α-Methyl-1H-imidazole-4-ethanaminedihydrobromide
    (S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid hydrochloride→(R)-(-)-α-Methylhistamine dihydrobromide,(R)-(-)-α-Methyl-1H-imidazole-4-ethanaminedihydrobromide

    Precursor

    L-histidinol
    methyl (2S)-2-amino-3-(1H-imidazol-5-yl)propanoate
    (2S)-1-Chloro-3-(1H-imidazol-5-yl)-2-propanamine
    (S)-(+)-4-(2-amino-3-chloropropyl)-imidazole dihydrochloride

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