Home > Chiral Compounds> (R)-2,5-Dihydro-3,6-diethoxy-2-isopropylpyrazine

(R)-2,5-Dihydro-3,6-diethoxy-2-isopropylpyrazine

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Origin: China

Cas No: 110117-71-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 110117-71-0 Formula: C11H20N2O2 Molecular Weight: 212.28900

Basic Info

Chemical Name	(R)-2,5-Dihydro-3,6-diethoxy-2-isopropylpyrazine
Synonyms	(2R)-3,6-diethoxy-2-propan-2-yl-2,5-dihydropyrazine;
CAS No.	110117-71-0
Molecular Formula	C11H20N2O2
Molecular Weight	212.28900
PSA	43.18000
LogP	0.76580

Properties

Appearance & Physical State	white solid
Density	1.06g/cm3
Boiling Point	282ºC at 760 mmHg
Flash Point	102.9ºC
Refractive Index	1.499
Vapor Pressure	0.00587mmHg at 25°C

Safety Info

HS Code	2933990090

Synthesis Route

Triethyloxonium tetrafluoroborate+(3R)-3-propan-2-ylpiperazine-2,5-dione→(R)-2,5-Dihydro-3,6-diethoxy-2-isopropylpyrazine
Boron trifluoride etherate+(3S)-3-propan-2-ylpiperazine-2,5-dione→(R)-2,5-Dihydro-3,6-diethoxy-2-isopropylpyrazine
(3R)-3-propan-2-ylpiperazine-2,5-dione+epichlorohydrin→(R)-2,5-Dihydro-3,6-diethoxy-2-isopropylpyrazine

Precursor

(3R)-3-propan-2-ylpiperazine-2,5-dione
Triethyloxonium tetrafluoroborate
Boron trifluoride etherate
(3S)-3-propan-2-ylpiperazine-2,5-dione

Downstream Product

Aliskiren inter-9

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