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(R)-(+)-1-Boc-3-aminopyrrolidine

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начало: Китай

Кас Но: 147081-49-0

Спецификация: 99%наименьший

минимальный объем заказа: 1 /kg

снабженческая способность: 50 mt/month

опережающий период: OEM 7 дней, пятно 3 дня

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Quick Details
CAS No.:
147081-49-0
Other Names:
N/A
MF:
C9H18N2O2
EINECS No.:
N/A
Place of Origin:
Shanghai, China
Type:
Agrochemical Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
99min%
Brand Name:
Richest
Model Number:
Richest
Application:
Pharmaceutical Raw Intermediates
Appearance:
N/A
Packing:
25kg/drum or 20kg/bag
Assay:
99.0 %min
Storage:
Room Temperature
Shelf life:
Proper Storage
Grade:
EP,USP,CP,JP
Brand:
Milliflux
Website:
www.milliflux.com
Origin:
China
Packaging&Delivery
Packaging Details
1kg/bag,25kg/bag,25kg/drum
Port
shanghai
Lead Time:
Quantity(Kilograms) 1 - 1 2 - 10 11 - 100 >100
Est. Time(days) 1 3 3 To be negotiated

Property

CAS No.: 147081-49-0 Formula: C9H18N2O2 Molecular Weight: 186.25100

Basic Info

Chemical Name	(R)-(+)-1-Boc-3-aminopyrrolidine
Synonyms	tert-butyl (R)-3-amino-pyrrolidine-1-carboxylate; (R)-(+)-1-Boc-3-Aminopyrrolidine; (R)-3-AMINO-N-BOC-PYRROLIDINE; (3R)-(+)-1-Boc-3-aminopyrrolidine; (R)-3-AMINO-1-N-BOC-PYRROLIDINE; (R)-(+)-N-BOC-3-aminopyrrolidine; (3R)-(+)-3-Amino-1-(tert-butoxycarbonyl)pyrrolidine; (R)-3-AMINO-1-BOC-PYRROLIDINE; (3R)-(+)-1-(tert-Butoxycarbonyl)-3-aminopyrrolidine; (R)-tert-Butyl 3-aminopyrrolidine-1-carboxylate; (R)-3-amino-N-(t-butoxycarbonyl)-pyrrolidine; (3R)-3-Aminopyrrolidine-1-carboxylic Acid T-butyl Ester; (3R)-3-amino-1-(tert-butoxycarbonyl)pyrrolidine; (R)-1-BOC-3-AMINOPYRROLIDINE; R-1-N-BOC-3-AMINO PYRROLIDINE; R-(+)-1-Boc-3-aminopyrrolidine; (3R)-(+)-3-Amino-1-Boc-pyrrolidine; tert-butyl (3R)-3-aminopyrrolidine-1-carboxylate; 1-Boc-3-(R)-aminopyrrolidine;
CAS No.	147081-49-0
Molecular Formula	C9H18N2O2
Molecular Weight	186.25100
PSA	55.56000
LogP	1.59270

Properties

Appearance & Physical State	colorless to light yellow liquid
Density	1.098
Boiling Point	243-244ºC
Melting Point	243-244ºC
Flash Point	196°F
Refractive Index	1.472

Safety Info

Safety Statements	26-36/37/39
HS Code	2942000000
RIDADR	UN 2810 6.1/PG 3
Risk Statements	R22
Hazard Codes	C; Xn

Synthesis Route

Benzophenone imine+tert-butoxycarbonyl anhydride→tert-Butyl carbamate+(R)-(+)-1-Boc-3-aminopyrrolidine
(R)-tert-butyl 3-azidopyrrolidine-1-carboxylate→(R)-(+)-1-Boc-3-aminopyrrolidine
(3R,αS)-N(1)-tert-butyloxycarbonyl-3-[N'-benzyl-N'-(α-methylbenzyl)amino]pyrrolidine→(R)-(+)-1-Boc-3-aminopyrrolidine

Precursor

(3R,αS)-N(1)-tert-butyloxycarbonyl-3-[N'-benzyl-N'-(α-methylbenzyl)amino]pyrrolidine
tert-butoxycarbonyl anhydride
(R)-tert-butyl 3-azidopyrrolidine-1-carboxylate
(S)-tert-butyl 3-(methylsulfonyloxy)pyrrolidine-1-carboxylate

Downstream Product

(R)-tert-Butyl 3-aminopyrrolidine-1-carboxylate hydrochloride
(R)-1-Boc-3-(Dimethylamino)Pyrrolidine
2-Methyl-2-propanyl 3-(isopropylamino)-1-pyrrolidinecarboxylate
tert-butyl 3-(ethylamino)pyrrolidine-1-carboxylate

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