Home > Chiral Compounds> Prostaglandin F2α tris salt

Prostaglandin F2α tris salt

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 38562-01-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

Products Specification
Product Description

Quick Details
CAS No.:
38562-01-5
Other Names:
PGF2a
MF:
C24H45NO8, C24H45NO8
EINECS No.:
254-002-3
Place of Origin:
Shandong, China
Type:
Endocrine System Agents
Grade Standard:
Medicine Grade
Brand Name:
HAIHANG
Model Number:
HHJH 38562-01-5
Purity:
96%~102%
Product Name:
Prostaglandin F2a tris salt
CAS:
38562-01-5
Appearance:
White Powder
MW:
475.62
Melting point:
-20°
form:
powder
Color:
white
Water:
<1%
Assay:
96%~102%
Packaging&Delivery
Packaging Details
Prostaglandin F2a tris salt ( Dinoprost trometamol ) CAS No 38562-01-5
Bags,1g,10g,100g,1kg, Or according to your requirement.
Port
Shanghai ,Qingdao , Dalian , Tianjing
Lead Time:
Quantity(Grams) 1 - 100 101 - 1000 1001 - 5000 >5000
Est. Time(days) 3 5 7 To be negotiated

Property

CAS No.: 38562-01-5 Formula: C24H45NO8 Molecular Weight: 475.61600

Description

Prostaglandin F2α (PGF2α in prostanoid nomenclature), pharmaceutically termed dinoprost (INN), is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient.
In domestic mammals, it is produced by the uterus when stimulated by oxytocin, in the event that there has been no implantation during the follicular phase. It acts on the corpus luteum to cause luteolysis, forming a corpus albicans and stopping the production of progesterone. Action of PGF2α is dependent on the number of receptors on the corpus luteum membrane.
The PGF2α isoform 8-iso-PGF2α was found in significantly increased amounts in patients with endometriosis, thus being a potential causative link in endometriosis-associated oxidative stress.

Basic Info

Chemical Name	Prostaglandin F2α tris salt
Synonyms	Dinoprost trometamol; Prostaglandin F2a tris salt;
CAS No.	38562-01-5
Molecular Formula	C24H45NO8
Molecular Weight	475.61600
PSA	184.70000
LogP	1.40400

Properties

Boiling Point	531ºC at 760 mmHg
Melting Point	25-35ºC
Flash Point	289ºC
Storage Condition	-20ºC

Safety Info

Safety Statements	53-45
HS Code	2937500000
Risk Statements	R60; R22
Hazard Codes	T
Symbol	GHS07, GHS08
Signal Word	Danger
Caution Statement	P201; P308 + P313
Hazard Declaration	H302; H360

Synthesis Route

(S)-3-((S)-2-(4,4-pentamethylene-3-(4-(3-(2-methylphenyl)ureido)benzyl)-2,5-dioxoimidazolidin-1-yl)-2-(2-methylpropyl)acetylamino)-3-phenylpropionic acid→Prostaglandin F2α tris salt
(S)-3-((S)-2-(4,4-pentamethylene-3-(4-(3-phenylureido)benzyl)-2,5-dioxoimidazolidin-1-yl)-2-(2-methylpropyl)acetylamino)-3-(4-methoxyphenyl)propionic acid→Prostaglandin F2α tris salt
(S)-3-((S)-2-(4,4-pentamethylene-3-(4-(3-phenylureido)benzyl)-2,5-dioxoimidazolidin-1-yl)-2-(2-methylpropyl)acetylamino)-3-(2,4-dimethoxyphenyl)propionic acid→Prostaglandin F2α tris salt

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	665 mg/kg	1.Behavioral-somnolence (general depressed activity) 2.Lungs, Thorax, or Respiration-respiratory depression 3.Skin and Appendages-hair
Intraperitoneal	LD50 - Lethal dose, 50 percent kill	Rodent - rat	101 mg/kg	1.Details of toxic effects not reported other than lethal dose value
Subcutaneous	LD50 - Lethal dose, 50 percent kill	Rodent - rat	66 mg/kg	1.Behavioral-altered sleep time (including change in righting reflex) 2.Behavioral-somnolence (general depressed activity) 3.Lungs, Thorax, or Respiration-respiratory stimulation

Precursor

(S)-3-((S)-2-(4,4-pentamethylene-3-(4-(3-phenylureido)benzyl)-2,5-dioxoimidazolidin-1-yl)-2-(2-methylpropyl)acetylamino)-3-(2,4-dimethoxyphenyl)propionic acid
(S)-3-((S)-2-(4,4-pentamethylene-3-(4-(3-(2-methylphenyl)ureido)benzyl)-2,5-dioxoimidazolidin-1-yl)-2-(2-methylpropyl)acetylamino)-3-phenylpropionic acid
(S)-3-((S)-2-(4,4-pentamethylene-3-(4-(3-phenylureido)benzyl)-2,5-dioxoimidazolidin-1-yl)-2-(2-methylpropyl)acetylamino)-3-(4-methoxyphenyl)propionic acid
(S)-3-((S)-2-(4,4-pentamethylene-3-(4-(3-(2-methylphenyl)ureido)benzyl)-2,5-dioxoimidazolidin-1-yl)-2-(2-methylpropyl)acetylamino)-3-(4-methoxyphenyl)propionic acid

Hot tags: prostaglandin f2α tris salt, China, manufacturers, suppliers, factory, wholesale, low price, high quality