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N,N-dimethylacetamide

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Origin: China

Cas No: 127-19-5

Specification: 99%min

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  • Products Specification
  • Product Description
  • Property

    CAS No.: 127-19-5 Formula: C4H9NO Molecular Weight: 87.12040

    Description

    Dimethylacetamide (DMA) is the organic compound with the formula CH3C(O)N(CH3)2. This colorless, water-miscible, high boiling liquid is commonly used as a polar solvent in organic synthesis. DMA is miscible with most other solvents, although it is poorly soluble in aliphatic hydrocarbons.

    Basic Info

    Chemical Name N,N-dimethylacetamide
    Synonyms

    N,N-Dimethylacetamide;
    Acetamide,N,N-dimethyl;
    Acetic acid-dimethylamide;
    Dimethylamide acetate;
    N,N-Dimethylethanamide;
    N-N-Dimethylacetamide;
    DIMETHYL ACETAMIDE;
    acetic acid dimethylamide;
    N-Acetyldimethylamine;
    Acetdimethylamide;
    DMA;
    Dimethylacetone amide;
    Acetamide, N,N-dimethyl-;
    N,N-Dimethylacetamid;
    N,N-dimethyl-acetamide;

    CAS No. 127-19-5
    Molecular Formula C4H9NO
    Molecular Weight 87.12040
    PSA 20.31000
    LogP 0.09450

    Properties

    Appearance & Physical State Clear, colorless liquid
    Density 0.937
    Boiling Point 164-166ºC
    Melting Point -20ºC
    Flash Point 66ºC
    Refractive Index 1.437-1.439
    Water Solubility miscible
    Stability Stable. Combustible. Incompatible with strong oxidizing agents.
    Storage Condition 0-6ºC
    Vapor Density 3.89 (vs air)
    Vapor Pressure 40 mm Hg ( 19.4 °C)

    Safety Info

    RTECS TX9625000
    Safety Statements S45-S53
    HS Code 2924199090
    WGK Germany 3
    RIDADR UN 1279 3/PG 2
    Risk Statements R20/21; R61
    Hazard Codes T
    Symbol GHS07, GHS08
    Caution Statement P201; P261; P280; P302 + P352 + P312; P304 + P340 + P312; P308 + P313
    Signal Word Danger
    Hazard Declaration H312 + H332; H319; H360D

    Synthesis Route

    N,N-dimethylacetamide compound with 1,1,1,3,3,3-hexafluoropropan-2-ol (1:1)N,N-dimethylacetamide+Hexafluoroisopropanol
    carbon monoxide+trimethylamineN-methylacetamide+N,N-dimethylacetamide
    N,N-dimethyl-N'-methylacetamidineN-methylacetamide+N,N-dimethylacetamide

    GC Analysis

    Column type Active phase Temperature (°C) Retention Index (I) Temperature Control Method
    Capillary OV-101 - 820. temperature ramp
    Capillary SPB-Sulfur - 833.3 temperature ramp
    Capillary DB-Wax - 1414. temperature ramp
    Capillary OV-101 - 833. temperature ramp
    Capillary DB-5 MS - 883. custom temperature program

    Precursor

    trimethylamine
    Tetramethylammonium iodide
    2-(dimethylamino)-1-phenylpropan-1-one
    carbon monoxide

    Downstream Product

    N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-3-oxobutanamide
    [(2S)-2-[(2R)-3,4-dihydroxy-5-oxo-2H-furan-2-yl]-2-hydroxyethyl] (6Z,9Z,12Z)-octadeca-6,9,12-trienoate
    3-(furan-2-yl)-N,N-dimethylprop-2-enamide
    N,N-dimethyl-2-phenylethenamine

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