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naphthalic anhydride

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Origin: China

Cas No: 81-84-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Quick Details
CAS No.:
81-84-5
Other Names:
1,8-Naphthalic anhydride 98%
MF:
C12H6O3
EINECS No.:
201-380-2
Place of Origin:
China
Type:
Agrochemical Intermediates, Dyestuff Intermediates, Pharmaceutical Intermediates, Syntheses Material Intermediates
Purity:
98%MIN
Brand Name:
Haihang
Model Number:
HHWXH-19112301
Application:
Organic synthesis intermediate
Appearance:
light yellow powder
Product name:
1,8-Naphthalic anhydride
Color:
light yellow
Packing:
25KG/BAG
Grade:
Industrial Grade
Usage:
Organic Synthesis
Molecular Weight:
198.17
Molecular formula:
C12H6O3
Storage:
Store below +30°C.
Sample:
available
COA:
available
Packaging&Delivery
Selling Units:
Single item
Single package size:
10X5X10 cm
Single gross weight:
1.500 kg
Lead Time:
Quantity(Kilograms) 1 - 100 >100
Est. Time(days) 3 To be negotiated

Property

CAS No.: 81-84-5 Formula: C12H6O3 Molecular Weight: 198.17400

Description

1,8-Naphthoic Anhydride is used in the synthesis of napthalimide analogues as anticancer agents.

Basic Info

Chemical Name	naphthalic anhydride
Synonyms	1,8-naphthalene dicarboxylic anhydride; protect(agrochemical); PROTECT(R); 1H,3H-Naphtho[1,8-cd]pyran-1,3-dione; 1,8-dinaphthoic anhydride; NAPHTHALIC ANHYDRIDE; naphthalene-1,8-dicarboxylic acid anhydride; 1H,3H-naphtho [1,8-cd]pyran-1,3-dione; naphthalene-1,8-dicarboxylic anhydride; 1,8-Naphthalic anhydride; 1,8-naphthalenedicarboxylic acid anhydride; 1,8-Naphthalic anhyd; Protect; naphthalic; 1,8-Naphthalic; pakarli;
CAS No.	81-84-5
Molecular Formula	C12H6O3
Molecular Weight	198.17400
PSA	43.37000
LogP	2.15040

Properties

Appearance & Physical State	pale yellow powder
Density	1.449 g/cm3
Boiling Point	407.5ºC at 760 mmHg
Melting Point	267-269ºC
Flash Point	272ºC
Refractive Index	1.736
Water Solubility	decomposes
Stability	Stable under normal temperatures and pressures. Moisture sensitive.
Storage Condition	Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Store protected from moisture.

Safety Info

RTECS	QK5350000
Safety Statements	S24/25
HS Code	29173980
WGK Germany	2
Risk Statements	R36/37/38
Hazard Codes	Xi
Symbol	GHS07
Hazard Declaration	H315; H319; H335
Signal Word	Warning
Caution Statement	P261; P305 + P351 + P338

Synthesis Route

acenaphthene→naphthalic anhydride
acenaphthoquinone→naphthalic anhydride
1,8-Diiodonaphthalene+carbon monoxide→naphthalic anhydride+2-methylbenzo[de]isoquinoline-1,3-dione

GC Analysis

Column type	Active phase	Temperature (°C)	Retention Index (I)	Temperature Control Method
Capillary	Methyl Silicone	-	1944.	custom temperature program
Capillary	HP-5	-	342.17	temperature ramp
Capillary	SPB-5	-	339.9	temperature ramp
Capillary	SPB-5	-	340.8	temperature ramp
Capillary	SE-30	-	341.19	temperature ramp

Toxicity

Exposure Route	Type of Test	Species Observed	Dose/Duration	Toxic Effects
Oral	LD50 - Lethal dose, 50 percent kill	Rodent - rat	12340 mg/kg	1.Details of toxic effects not reported other than lethal dose value

Precursor

N,O-Dimethylhydroxylamine hydrochloride
acenaphthoquinone
1,8-Diiodonaphthalene
acenaphthene

Downstream Product

11-methoxy-benzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one
2-(1,3-dioxobenzo[de]isoquinolin-2-yl)acetic acid
10-methoxy-benzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one
2-(2-hydroxyethyl)benzo[de]isoquinoline-1,3-dione

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