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N-tert-butyl-3-[4-(2-methoxyphenyl)piperazin-1-yl]-2-phenylpropanamide

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Origin: China

Cas No: 133025-23-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 133025-23-7 Formula: C24H35Cl2N3O2 Molecular Weight: 468.46000

Description

WAY-100,135 is a serotonergic drug of the phenylpiperazine family which is used in scientific research. It acts as potent 5-HT1A receptor antagonist, and was originally believed to be highly selective, but further studies have demonstrated that it also acts as a partial agonist of the 5-HT1D receptor (pKi = 7.58; virtually the same affinity for 5-HT1A), and to a much lesser extent, of the 5-HT1B receptor (pKi = 5.82). These findings may have prompted the development of the related compound WAY-100,635, another purportedly selective and even more potent 5-HT1A antagonist, which was synthesized shortly thereafter. However, WAY-100,635 turned out to be non-selective as well, having been shown to act additionally as a potent D4 receptor agonist later on.

Basic Info

Chemical Name	N-tert-butyl-3-[4-(2-methoxyphenyl)piperazin-1-yl]-2-phenylpropanamide
Synonyms
CAS No.	133025-23-7
Molecular Formula	C24H35Cl2N3O2
Molecular Weight	468.46000
PSA	44.81000
LogP	5.51350

Properties

Density	1.085g/cm3
Boiling Point	582.8ºC at 760mmHg
Flash Point	306.3ºC
Refractive Index	1.556
Vapor Pressure	1.43E-13mmHg at 25°C

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