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N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine

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Origin: China

Cas No: 93102-05-7

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 93102-05-7 Formula: C13H23NOSi Molecular Weight: 237.41300

Description

N-(Methoxymethyl)-N-[(trimethylsilyl)methyl]benzenemethanamine is used in the synthesis of pyrrolidine derivatives as novel sodium channel blockers used to treat ischemic related ailments.

Basic Info

Chemical Name	N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine
Synonyms	N-(methoxymethyl)-1-phenyl-N-(trimethylsilylmethyl)methanamine;
CAS No.	93102-05-7
Molecular Formula	C13H23NOSi
Molecular Weight	237.41300
PSA	12.47000
LogP	3.38820

Properties

Appearance & Physical State	clear colorless to light yellow liquid
Density	0.928
Boiling Point	76ºC (0.3 mmHg)
Flash Point	66ºC
Refractive Index	1.4915-1.4935
Storage Condition	Refrigerator

Safety Info

Safety Statements	S26-S37/39
HS Code	2931900090
WGK Germany	3
Risk Statements	R36/37/38
Hazard Codes	Xi
Signal Word	Warning
Hazard Declaration	H315; H319; H335
Symbol	GHS07
Caution Statement	P261; P305 + P351 + P338

Synthesis Route

Formaldehyde+N-(Trimethylsilylmethyl)benzylamine→N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine
Methanol+Formaldehyde→N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine
Methanol+N-(Trimethylsilylmethyl)benzylamine→N-(Methoxymethyl)-N-(trimethylsilylmethyl)benzylamine

Precursor

N-(Trimethylsilylmethyl)benzylamine
butyllithium
Formaldehyde
chloro(methoxy)methane

Downstream Product

3-(1-benzylpyrrolidin-3-yl)pyridine
2-(1-benzylpyrrolidin-3-yl)pyridine
Ethyl 1-Benzylpyrrolidine-3-carboxylate
cis-5-Benzyltetrahydropyrrolo[3,4-c]pyrrole-1,3(2H,3aH)-dione

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