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N-Carbamoyl-4-methylbenzenesulfonamide

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Origin: China

Cas No: 1694-06-0

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 1694-06-0 Formula: C8H10N2O3S Molecular Weight: 214.24200

Description

N-(p-Toluenesulfonyl)urea is used in the synthesis of Glyburide, a second generation sulfonylurea with hypoglycemic activity. Glyburide is an antidiabetic agent.

Basic Info

Chemical Name	N-Carbamoyl-4-methylbenzenesulfonamide
Synonyms	p-Toluenesulfonylurea; (4-methylphenyl)sulfonylurea; N-(p-Toluenesulfonyl)urea;
CAS No.	1694-06-0
Molecular Formula	C8H10N2O3S
Molecular Weight	214.24200
PSA	97.64000
LogP	2.52400

Properties

Appearance & Physical State	white crystalline powder
Density	1.363g/cm3
Melting Point	196-198ºC
Refractive Index	1.579

Safety Info

Safety Statements	S26-S36/37/39-S45
HS Code	2935009090
Risk Statements	R34
Hazard Codes	C

Synthesis Route

N1-tosyl-N2-nitroguanidine→N-Carbamoyl-4-methylbenzenesulfonamide
p-Toluenesulfonyl chloride→N-Carbamoyl-4-methylbenzenesulfonamide
toluene-4-sulfonamide→N-Carbamoyl-4-methylbenzenesulfonamide

Precursor

urea
N1-tosyl-N2-nitroguanidine
N-p-Toluolsulfonyl-N'-formyl-harnstoff
toluene-4-sulfonamide

Downstream Product

3,3'-iminodipropanoic acid tosylamide
cyanuric acid

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