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N-acetylsphingosine

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Origin: China

Cas No: 3102-57-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 3102-57-6 Formula: C20H39NO3 Molecular Weight: 341.52900

Description

A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2.

Basic Info

Chemical Name	N-acetylsphingosine
Synonyms	N-Acetyl-D-sphingosine; N-Ethanoyl-D-erythro-sphingosine; D-erythro-N-acetyl-sphingosine; C14 SPHINGOID BASE; C2:0 CERAMIDE; CERAMIDE C2; N-ACETYLSPHINGOSINE; C2-D-ERYTHRO-CERAMIDE; ACETYL CERAMIDE; N-acetyl-sphing-4-enine; Ceramide,N-Acetylsphingosine; TOC Ceramide; N-acetyl-d-erythro-sphingosine; C2 CERAMIDE;
CAS No.	3102-57-6
Molecular Formula	C20H39NO3
Molecular Weight	341.52900
PSA	69.56000
LogP	4.49250

Properties

Density	0.964g/cm3
Boiling Point	532.4ºC at 760mmHg
Melting Point	93-96ºC
Flash Point	275.8ºC
Refractive Index	1.484
Storage Condition	-20ºC

Safety Info

Safety Statements	S22-S24/25
HS Code	2924199090

Synthesis Route

sphingosine+acetyl chloride→N-acetylsphingosine
sphingosine+Acetic anhydride→N-acetylsphingosine
erythro-N-acetyl-1-O-benzoylsphingosine→N-acetylsphingosine

Precursor

erythro-N-acetyl-1-O-benzoylsphingosine
acetyl chloride
Acetic anhydride
(4S)-3-acetyl-4r-hydroxymethyl-5c-pentadec-1-en-t-yl-2ξ-phenyl-oxazolidine

Downstream Product

sphingosine
N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]acetamide

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