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N-[(1R,2R)-3-[tert-butyl(dimethyl)silyl]oxy-1-hydroxy-1-(4-nitrophenyl)propan-2-yl]-2,2-dichloroacetamide

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Origin: China

Cas No: 864529-25-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

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CAS No.: 864529-25-9 Formula: C17H26Cl2N2O5Si Molecular Weight: 437.39000

Description

Used in the preparation of Azithromycin compounds as antibacterial, anti-proliferative, and antiinflammatory agents.

Basic Info

Chemical Name	N-[(1R,2R)-3-[tert-butyl(dimethyl)silyl]oxy-1-hydroxy-1-(4-nitrophenyl)propan-2-yl]-2,2-dichloroacetamide
Synonyms	Chloramphenicol O-tert-Butyldimethylsilyl Ether;
CAS No.	864529-25-9
Molecular Formula	C17H26Cl2N2O5Si
Molecular Weight	437.39000
PSA	107.87000
LogP	5.30200

Synthesis Route

chloramphenicol+tert-butyldimethylsilyl chloride→N-[(1R,2R)-3-[tert-butyl(dimethyl)silyl]oxy-1-hydroxy-1-(4-nitrophenyl)propan-2-yl]-2,2-dichloroacetamide

Precursor

tert-butyldimethylsilyl chloride
chloramphenicol

Downstream Product

[(1S,2R)-3-[tert-butyl(dimethyl)silyl]oxy-2-[(2,2-dichloroacetyl)amino]-1-(4-nitrophenyl)propyl] acetate

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