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Methyl 4-Amino-2-Chlorobenzoate

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Origin: China

Cas No: 46004-37-9

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property

CAS No.: 46004-37-9 Formula: C8H8ClNO2 Molecular Weight: 185.60800

Description

Methyl 4-Amino-2-chlorobenzoate is used as a reagent to synthesize selective LXR agonists that increase HDL levels and reverse cholesterol transport in mice.

Basic Info

Chemical Name	Methyl 4-Amino-2-Chlorobenzoate
Synonyms	Methyl 4-amino-2-chlorobenzoate;
CAS No.	46004-37-9
Molecular Formula	C8H8ClNO2
Molecular Weight	185.60800
PSA	52.32000
LogP	2.29000

Properties

Appearance & Physical State	White to off-white powder
Density	1.311g/cm3
Boiling Point	334.207ºC at 760 mmHg
Melting Point	112-114ºC
Flash Point	155.923ºC
Refractive Index	1.581

Safety Info

HS Code	2922499990

Synthesis Route

METHYL 2-CHLORO-4-NITROBENZOATE→Methyl 4-Amino-2-Chlorobenzoate
Methanol+4-amino-2-chlorobenzoic acid→Methyl 4-Amino-2-Chlorobenzoate
4-amino-2-chlorobenzoic acid+dimethyl sulfate→Methyl 4-Amino-2-Chlorobenzoate

Precursor

METHYL 2-CHLORO-4-NITROBENZOATE
acetyl chloride
dimethyl sulfate
4-amino-2-chlorobenzoic acid

Downstream Product

N-[3-chloro-4-(6,11-dihydropyrrolo[2,1-c][1,4]benzodiazepine-5-carbonyl)phenyl]-5-fluoro-2-methylbenzamide
2-chloro-4-sulfamoylbenzoic acid
2-chloro-4-[(5-fluoro-2-methylbenzoyl)amino]benzoic acid

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