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Picture of Methyl (2S)-1-(tert-butoxycarbonyl)pyroglutamate

Methyl (2S)-1-(tert-butoxycarbonyl)pyroglutamate

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Origin: China

Cas No: 108963-96-8

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

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  • Products Specification
  • Product Description
  • Quick Details

    CAS No.:
    108963-96-8
    Other Names:
    BOC-PYR-OME
    MF:
    C11H17NO5
    EINECS No.:
    NA
    Place of Origin:
    Shanghai, China
    Type:
    Pharmaceutical Intermediates, Syntheses Material Intermediates, Chiral Reagents
    Purity:
    98% min
    Brand Name:
    SHXL
    Model Number:
    SHXLAPI000216
    Application:
    Pharm Intermediates
    Appearance:
    Solid
    Product name:
    Boc-L-Pyroglutamic acid methyl ester
    CAS:
    108963-96-8
    Molecular Weight:
    243.26
    Melting point:
    69-71 °C
    Storage:
    2-8°C
    Solubility:
    Soluble in dichloromethane
    Usage:
    Pharmaceutical Intermediates
    Brand:
    Xinglu

    Packaging&Delivery

    Packaging Details
    1kg/bag
    Port
    Shanghai, China
  • Property

    CAS No.: 108963-96-8 Formula: C11H17NO5 Molecular Weight: 243.25600

    Basic Info

    Chemical Name Methyl (2S)-1-(tert-butoxycarbonyl)pyroglutamate
    Synonyms

    1-O-tert-butyl 2-O-methyl (2S)-5-oxopyrrolidine-1,2-dicarboxylate;
    Methyl Boc-L-Pyroglutamate;
    Boc-pGlu-OMe;
    Methyl (S)-N-(tert-butoxycarbonyl)pyroglutamate;
    Methyl (2S)-1-(tert-butoxycarbonyl)py;
    Methyl (S)-Boc-5-pyrrolidone-2-carboxylate;
    Boc-L-Pyroglutamic acid methyl ester;
    Boc-Pyr-Ome;
    (S)-1-tert-Butyl 2-methyl 5-oxopyrrolidine-1,2-dicarboxylate;

    CAS No. 108963-96-8
    Molecular Formula C11H17NO5
    Molecular Weight 243.25600
    PSA 72.91000
    LogP 1.02340

    Properties

    Density 1.209g/cm3
    Boiling Point 361.6ºC at 760 mmHg
    Melting Point 69-71ºC
    Flash Point 172.5ºC
    Refractive Index 1.487
    Vapor Pressure 2.04E-05mmHg at 25°C

    Safety Info

    HS Code 2933790090

    Synthesis Route

    tert-butoxycarbonyl anhydride+Methyl L-PyroglutamateMethyl (2S)-1-(tert-butoxycarbonyl)pyroglutamate
    Methanol+tert-butoxycarbonyl anhydrideMethyl (2S)-1-(tert-butoxycarbonyl)pyroglutamate
    Methanol+tert-butoxycarbonyl anhydrideMethyl (2S)-1-(tert-butoxycarbonyl)pyroglutamate

    Precursor

    5-oxo-L-proline
    tert-butoxycarbonyl anhydride
    Methyl L-Pyroglutamate
    Methanol

    Downstream Product

    Methyl (2S,4R)-1-(tert-butoxycarbonyl)-4-methylpyroglutamate
    (2S,5S)-5-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
    (2S,4R)-4-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
    Methyl L-Pyroglutamate

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