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L-threo-Dihydrosphingosine

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Origin: China

Cas No: 15639-50-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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CAS No.: 15639-50-6 Formula: C18H39NO2 Molecular Weight: 301.50800

Description

Safingol is a lyso-sphingolipid protein kinase inhibitor. It has the molecular formula C18H39NO2 and is a colorless solid. Medicinally, safingol has demonstrated promising anticancer potential as a modulator of multi-drug resistance and as an inducer of necrosis. The administration of safingol alone has not been shown to exert a significant effect on tumor cell growth. However, preclinical and clinical studies have shown that combining safingol with conventional chemotherapy agents such as fenretinide, vinblastine, irinotecan and mitomycin C can dramatically potentiate their antitumor effects. Currently in Phase I clinical trials, it is believed to be safe to co-administer with cisplatin.

Basic Info

Chemical Name	L-threo-Dihydrosphingosine
Synonyms	L-threo sphinganine,2S,3S) L-threo-2-amino-1,3-octadecanediol; L-THREO-DIHYDROSPHINGOSINE;
CAS No.	15639-50-6
Molecular Formula	C18H39NO2
Molecular Weight	301.50800
PSA	66.48000
LogP	4.84850