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L(+)-Leucinol

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Origin: China

Cas No: 7533-40-6

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 80 mt/month

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 7533-40-6 Formula: C6H15NO Molecular Weight: 117.18900

    Description

    (S)-2-Amino-4-methylpentanol is a starting material for the synthesis of aminopeptidase N and phospholipase A2 inhibitors.

    Basic Info

    Chemical Name L(+)-Leucinol
    Synonyms

    (S)-LEUCINOL;
    H-LEUCINOL;
    L-(S)-leucinol;
    H-LEU-OL;
    H-L-LEU-OL;
    L-Leucinol;
    1-Pentanol, 2-amino-4-methyl-, (S)-;
    (S)-2-amino-4-methyl-1-pentanol;
    (1S)-1-(hydroxymethyl)-3-methylbutylamine;
    (S)-2-amino-4-methylpentanol;
    (2S)-2-amino-4-methylpentanol;
    L-Leu-ol;

    CAS No. 7533-40-6
    Molecular Formula C6H15NO
    Molecular Weight 117.18900
    PSA 46.25000
    LogP 1.05240

    Properties

    Appearance & Physical State clear colorless to slightly yellow liquid
    Density 0.917
    Boiling Point 208-210ºC
    Melting Point 66 - 70ºC
    Flash Point 90ºC
    Refractive Index 1.4496-1.4516
    Storage Condition Store at 0ºC

    Safety Info

    Safety Statements S26-S36
    HS Code 2922199090
    WGK Germany 3
    Risk Statements R36/37/38
    Hazard Codes Xi
    Caution Statement P261; P305 + P351 + P338
    Symbol GHS07
    Hazard Declaration H315; H319; H335
    Signal Word Warning

    Synthesis Route

    methyl L-leucinate→L(+)-Leucinol
    Methyl L-leucinate hydrochloride→L(+)-Leucinol
    L-leucine→L(+)-Leucinol

    Precursor

    methyl L-leucinate
    L-leucine
    (-)-(3R,5S)-5-(2-methylpropyl)-3-phenylmorpholin-2-one
    ethyl (2S)-2-amino-4-methylpentanoate

    Downstream Product

    tert-butyl N-[(2S)-1-hydroxy-4-methylpentan-2-yl]carbamate
    (2R)-4-methyl-2-(phenylmethoxycarbonylamino)pentanoic acid
    1-Phenyl-1-propanol
    4-Butylaniline

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