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L-LEUCINE β-NAPHTHYLAMIDE

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Origin: China

Cas No: 732-85-4

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 50 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Product Description

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CAS No.: 732-85-4 Formula: C16H20N2O Molecular Weight: 256.34300

Description

L-Leucine-β-naphthylamide is used in the synthesis of protein tyrosine phosphatase inhibitors. Used as an agent to combat Leishmania major.

Basic Info

Chemical Name	L-LEUCINE β-NAPHTHYLAMIDE
Synonyms	H-LEU-BETANA; LEUCINE-BETANA; H-Leu-bNA; L-Leucin-[2]naphthylamid; (S)-2-amino-4-methyl-pentanoic acid naphthalene-2-ylamide; L-Leu-NNap; L-LEUCINE-2-NAPHTHYLAMIDE;
CAS No.	732-85-4
Molecular Formula	C16H20N2O
Molecular Weight	256.34300
PSA	55.12000
LogP	3.92500

Properties

Density	1.128 g/cm3
Boiling Point	467ºC at 760 mmHg
Flash Point	236.2ºC
Refractive Index	1.625
Storage Condition	-20ºC

Safety Info

Safety Statements	S22; S36
Risk Statements	R40
Hazard Codes	Xn
Signal Word	Warning
Symbol	GHS08
Hazard Declaration	H351
Caution Statement	P281

Synthesis Route

benzyl N-[(2S)-4-methyl-1-(naphthalen-2-ylamino)-1-oxopentan-2-yl]carbamate→L-LEUCINE β-NAPHTHYLAMIDE
N-benzyloxycarbonyl-L-leucine→L-LEUCINE β-NAPHTHYLAMIDE
PHT-LEU-OH→L-LEUCINE β-NAPHTHYLAMIDE

Precursor

PHT-LEU-OH
benzyl N-[(2S)-4-methyl-1-(naphthalen-2-ylamino)-1-oxopentan-2-yl]carbamate
N-benzyloxycarbonyl-L-leucine

Downstream Product

L-leucine
2-naphthylamine

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