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Home > Chiral Compounds> L-6-Hydroxy Norleucine
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L-6-Hydroxy Norleucine

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Origin: China

Cas No: 6033-32-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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  • Products Specification
  • Product Description

  • Property

    CAS No.: 6033-32-5 Formula: C6H13NO3 Molecular Weight: 147.17200

    Description

    A key chiral intermediate used for synthesis of a vasopeptidase inhibitor.

    Basic Info

    Chemical Name L-6-Hydroxy Norleucine
    Synonyms

    L-6-HYDROXYNORLEUCINE;

    CAS No. 6033-32-5
    Molecular Formula C6H13NO3
    Molecular Weight 147.17200
    PSA 83.55000
    LogP 0.26120

    Properties

    Density 1.189g/cm3
    Boiling Point 361.7ºC at 760mmHg
    Flash Point 172.6ºC
    Refractive Index 1.644

    Safety Info

    HS Code 2922509090

    Synthesis Route

    ethyl 6-(tert-butyldimethylsilyloxy)-2-oxohexanoate→L-6-Hydroxy Norleucine
    2(S)-2-(benzyloxycarbonylamino)-6-hydroxyhexanoic acid→L-6-Hydroxy Norleucine
    5-(4-hydroxybutyl)imidazolidine-2,4-dione→L-6-Hydroxy Norleucine

    Precursor

    (S)-2-(2-oxooxepan-3-yl)isoindoline-1,3-dione
    ethyl 6-(tert-butyldimethylsilyloxy)-2-oxohexanoate
    2(S)-2-(benzyloxycarbonylamino)-6-hydroxyhexanoic acid
    5-(4-hydroxybutyl)imidazolidine-2,4-dione

    Downstream Product

    (2S)-6-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
    (2S)-2-(phenylmethoxycarbonylamino)hexanedioic acid
    (2S)-6-oxopiperidine-2-carboxylic acid
    N-{[(2S)-6-Oxo-2-piperidinyl]carbonyl}-L-leucyl-L-prolinamide

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