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L-6-Hydroxy Norleucine

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Origin: China

Cas No: 6033-32-5

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

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Products Specification
Product Description

Property
CAS No.: 6033-32-5 Formula: C6H13NO3 Molecular Weight: 147.17200

Description
A key chiral intermediate used for synthesis of a vasopeptidase inhibitor.

Basic Info

Chemical Name L-6-Hydroxy Norleucine

Synonyms
L-6-HYDROXYNORLEUCINE;

CAS No. 6033-32-5

Molecular Formula C6H13NO3

Molecular Weight 147.17200

PSA 83.55000

LogP 0.26120

Properties

Density 1.189g/cm3

Boiling Point 361.7ºC at 760mmHg

Flash Point 172.6ºC

Refractive Index 1.644

Safety Info

HS Code 2922509090

Synthesis Route
ethyl 6-(tert-butyldimethylsilyloxy)-2-oxohexanoate→L-6-Hydroxy Norleucine
2(S)-2-(benzyloxycarbonylamino)-6-hydroxyhexanoic acid→L-6-Hydroxy Norleucine
5-(4-hydroxybutyl)imidazolidine-2,4-dione→L-6-Hydroxy Norleucine

Precursor
(S)-2-(2-oxooxepan-3-yl)isoindoline-1,3-dione
ethyl 6-(tert-butyldimethylsilyloxy)-2-oxohexanoate
2(S)-2-(benzyloxycarbonylamino)-6-hydroxyhexanoic acid
5-(4-hydroxybutyl)imidazolidine-2,4-dione

Downstream Product
(2S)-6-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
(2S)-2-(phenylmethoxycarbonylamino)hexanedioic acid
(2S)-6-oxopiperidine-2-carboxylic acid
N-{[(2S)-6-Oxo-2-piperidinyl]carbonyl}-L-leucyl-L-prolinamide

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