Welcome to GlobalChemMall

ALL CATEGORIES
Categories
0
Wishlist
Home > Chiral Compounds> ICI 199,441 hydrochloride,2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride
Picture of ICI 199,441 hydrochloride,2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride

ICI 199,441 hydrochloride,2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride

Get Latest Price >

FOB Price contact us for price

Origin: China

Cas No: 115199-84-3

Specification: 99%min

Min order Quantity: 1 /kg

Supply Ability: 100 mt/month

Lead time: 7 days for OEM, 3 days for ready goods

Vendor:

Payment Terms:

Inquiry now

* Send an Inquiry to us

Add to wishlist

* Name your price
* Start order doesn't mean buying now

  • Products Specification
  • Product Description

  • Property

    CAS No.: 115199-84-3 Formula: C21H25Cl3N2O Molecular Weight: 427.79500

    Description

    ICI-199,441 is a drug which acts as a potent and selective κ-opioid agonist, and has analgesic effects. It is a biased agonist of the KOR, and is one of a relatively few KOR ligands that is G protein-biased rather than β-arrestin-biased.

    Basic Info

    Chemical Name ICI 199,441 hydrochloride,2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride
    Synonyms

    ICI 199,441 HYDROCHLORIDE;
    ICI 199,441;

    CAS No. 115199-84-3
    Molecular Formula C21H25Cl3N2O
    Molecular Weight 427.79500
    PSA 23.55000
    LogP 5.57130

    Properties

    Boiling Point 532.8ºC at 760mmHg
    Flash Point 276ºC
    Vapor Pressure 1.97E-11mmHg at 25°C

    Synthesis Route

    (S)-2-(methoxycarbonylamino)-2-phenylacetic acid→ICI 199,441 hydrochloride,2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride
    →ICI 199,441 hydrochloride,2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride
    (1S)-N-methyl-1-phenyl-2-(pyrrolidin-1-yl)ethanamine+Benzeneacetyl chloride, 3,​4-​dichloro-→ICI 199,441 hydrochloride,2-(3,4-Dichlorophenyl)-N-methyl-N-[(1S)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride

    Precursor


    (S)-2-(methoxycarbonylamino)-2-phenylacetic acid
    (1S)-N-methyl-1-phenyl-2-(pyrrolidin-1-yl)ethanamine
    Benzeneacetyl chloride, 3,​4-​dichloro-

Hot tags: ici 199,441 hydrochloride,2-(3,4-dichlorophenyl)-n-methyl-n-[(1s)-1-phenyl-2-(1-pyrrolidinyl)ethyl]acetamidehydrochloride, China, manufacturers, suppliers, factory, wholesale, low price, high quality
You may also like