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HitGen Inc.

Company Profile

HitGen Inc. is a biotech company headquartered in Chengdu, China, with subsidiaries in Cambridge, UK and Houston, USA. It became a publicly listed company in Shanghai Stock Exchange in April 2020 (ticker code 688222.SH).  HitGen has established a drug discovery research platform for small molecules and nucleic acid drug centered on the design, synthesis and screening of DNA encoded chemical libraries (DELs), fragment-based drug discovery (FBDD) and structure-based drug design (SBDD) technologies. HitGen's DELs currently contains more than 1 trillion novel, diverse, drug-like small molecules and macrocyclic compounds. These compounds are members of DELs synthesized from many thousands of distinct chemical scaffolds, designed with tractable chemistry, and have yielded proven results for the discovery of small molecule leads against precedented and unprecedented classes of biological targets.

Core engineers and technicians

2001.09-2005.06Pharmaceutical Engineering, Wuhan Engineering University;
2005.06-2007.08 he was engaged in the design of pharmaceutical factory in Wuhan Kaijie Pharmaceutical Design Institute
2007.09-2010.06 majored in biochemical engineering at Wuhan University of Technology, studying for a master's degree
2010.07-2014.05 in Hubei Liyi Technology Co., Ltd., a subsidiary of China Pharmaceutical
2014.06-2015.05 in Wuhan WuXi PharmaTech Co., Ltd.
2015.06-present  Silechenger (Wuhan) Technology Co., Ltd.
2001.09-2005.06Pharmaceutical Engineering, Wuhan Engineering University;
2005.06-2007.08 he was engaged in the design of pharmaceutical factory in Wuhan Kaijie Pharmaceutical Design Institute
2007.09-2010.06 majored in biochemical engineering at Wuhan University of Technology, studying for a master's degree
2010.07-2014.05 in Hubei Liyi Technology Co., Ltd., a subsidiary of China Pharmaceutical
2014.06-2015.05 in Wuhan WuXi PharmaTech Co., Ltd.
2015.06-present  Silechenger (Wuhan) Technology Co., Ltd.
 

Chemical Reactions

  • Azidation

  • bromination reaction

  • palladium catalyzed coupling

Production facilities

High and low temperature reaction kettle, rotary evaporator, extraction kettle, refrigerator, blast drying oven, vacuum drying oven, high performance liquid chromatography, melting point apparatus, ultraviolet detector

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